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Biocryst Pharmaceuticals (BCRX) Q1 2025 earnings results (first quarter 2025)

10-Q filed May 6, 2025

Biocryst Pharmaceuticals (BCRX) reported revenue of $146M for the first quarter 2025 (Q1 2025), +57% from a year earlier and +11% from the quarter before. Operating margin was 14.6%, net earnings $32K (0.0% of revenue).

Revenue$146M
Year over year+57%
Quarter over quarter+11%
Operating margin14.6%
Net earnings$32K

Biocryst Pharmaceuticals, Q1 2025: revenue $146M (+57% year over year), operating margin 14.6%, net earnings $32K, operating cash flow −$27.5M. The chart follows the revenue to costs, profit and cash.

Q1 2025AmountQ/QY/Y
Revenue$146M+11%+57%
Operating profit$21.2M——
Net earnings$32K——
Operating cash flow−$27.5M——

What changed

Revenue was $145.5M in Q1 2025, up 57% year over year and up 11% from the previous quarter. ORLADEYO was the largest line at 92% of revenue. ORLADEYO added $45.4M year over year (up 51%), 86% of the total change.

Operating profit was $21.2M, a 14.6% margin (up 30.2 points year over year). Total costs grew 16% against revenue growth of 57%. The fastest-growing cost line was Cost of revenue (+261%). Net earnings were $32K. The effective tax rate was 95.8%.

Operating cash flow was −$27.5M. Non-cash charges added back $331K of depreciation and amortization and $21.4M of share-based compensation. Working capital and other items used $49.2M. Capital expenditures of $143K exceeded it, leaving free cash flow of −$27.7M.

Questions

What was Biocryst Pharmaceuticals' revenue in the first quarter 2025?

Biocryst Pharmaceuticals (BCRX) reported revenue of $146M for the first quarter 2025 (Q1 2025), +57% from a year earlier and +11% from the quarter before.

Was Biocryst Pharmaceuticals profitable in the first quarter 2025?

Operating profit was $21.2M (14.6% of revenue) and net earnings $32K.

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Source: Biocryst Pharmaceuticals 10-Q on SEC EDGAR.