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Biocryst Pharmaceuticals (BCRX) Q2 2025 earnings results (second quarter 2025)

10-Q filed Aug 5, 2025

Biocryst Pharmaceuticals (BCRX) reported revenue of $163M for the second quarter 2025 (Q2 2025), +49% from a year earlier and +12% from the quarter before. Operating margin was 18.2%, net earnings $5.1M (3.1% of revenue).

Revenue$163M
Year over year+49%
Quarter over quarter+12%
Operating margin18.2%
Net earnings$5.1M

Biocryst Pharmaceuticals, Q2 2025: revenue $163M (+49% year over year), operating margin 18.2%, net earnings $5.1M, operating cash flow $41.3M. The chart follows the revenue to costs, profit and cash.

Q2 2025AmountQ/QY/Y
Revenue$163M+12%+49%
Operating profit$29.8M+40%+240%
Net earnings$5.1M159×—
Operating cash flow$41.3M——
Free cash flow$41.1M——

What changed

Revenue was $163.4M in Q2 2025, up 49% year over year and up 12% from the previous quarter. ORLADEYO was the largest line at 96% of revenue. ORLADEYO added $48.5M year over year (up 45%), 90% of the total change.

Operating profit was $29.8M, a 18.2% margin (up 10.2 points year over year). Of the extra revenue versus a year earlier, 39% reached operating profit, above the 8% margin then. Total costs grew 33% against revenue growth of 49%. The fastest-growing cost line was Cost of revenue (+65%). Net earnings were $5.1M. The effective tax rate was 21.6%.

Operating cash flow was $41.3M, 812% of net earnings. Non-cash charges added back $329K of depreciation and amortization and $21.3M of share-based compensation. Working capital and other items added $14.6M. Capital expenditures of $179K left free cash flow of $41.1M.

Questions

What was Biocryst Pharmaceuticals' revenue in the second quarter 2025?

Biocryst Pharmaceuticals (BCRX) reported revenue of $163M for the second quarter 2025 (Q2 2025), +49% from a year earlier and +12% from the quarter before.

Was Biocryst Pharmaceuticals profitable in the second quarter 2025?

Operating profit was $29.8M (18.2% of revenue) and net earnings $5.1M.

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Source: Biocryst Pharmaceuticals 10-Q on SEC EDGAR.