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How BillionToOne (BLLN) makes money

BillionToOne (BLLN) made $123M of revenue in the third quarter 2026 (Q3 2026), +47% from a year earlier. Prenatal brought in $104M (85%); Oncology brought in $17.1M (14%); Clinical trial support and other services brought in $1.6M (1%). Of every dollar of revenue, 71¢ was left as gross profit, 9¢ was left as operating profit, 14¢ was left as net earnings.

Drawing the Sankey…

BillionToOne revenue by segment, Q3 2026BillionToOne revenue by segment, Q3 2026Prenatal$104MOncology$17.1MClinical trial support and other …$1.6M
BillionToOne: revenue by line, Q3 2025 to Q3 2026BillionToOne: revenue by line, Q3 2025 to Q3 2026PrenatalOncologyClinical trial suppor…Prenatal: $104M latest$104MOncology: $17.1M latest$17.1MClinical trial support and other services: $1.6M latestQ3 2025Q4 2025Q1 2026Q2 2026Q3 2026
Prenatal went from 89% of revenue in Q3 2025 to 85% in Q3 2026, the largest shift in the mix.
BillionToOne revenue by quarterBillionToOne revenue by quarter$83.5MQ3 2025$96.1MQ4 2025$108MQ1 2026$109MQ2 2026$123MQ3 2026
BillionToOne: where each dollar of revenue goesBillionToOne: where each dollar of revenue goesCost of revenue29¢Gross profit71¢Operating expenses62¢Operating profit9¢Income tax0¢Net earnings14¢Operating cash flow10¢Free cash flow7¢

Revenue by segment, Q3 2026

SegmentRevenueShareQ/QY/Y
Prenatal$104M84.8%+11%+41%
Oncology$17.1M13.9%+25%+96%
Clinical trial support and other services$1.6M1.3%+7%+115%

Where each dollar of revenue goes

LineQ3 2026% of revenue
Revenue$123M100.0%
Cost of revenue$35.8M29.1%
Gross profit$87.1M70.9%
Operating expenses$76.1M61.9%
Operating profit$11.0M9.0%
Income tax$1K0.0%
Net earnings$17.4M14.1%
Operating cash flow$12.5M10.2%
Free cash flow$8.6M7.0%

Revenue, quarter by quarter

QuarterRevenueY/Y
Q3 2026$123M+47%
Q2 2026$109M+64%
Q1 2026$108M+84%
Q4 2025$96.1M+113%
Q3 2025$83.5M+117%

From BillionToOne's 10-Q filed Nov 4, 2026 (on EDGAR).

Questions

How does BillionToOne make money?

BillionToOne (BLLN) made $123M of revenue in the third quarter 2026 (Q3 2026), +47% from a year earlier. Prenatal brought in $104M (85%); Oncology brought in $17.1M (14%); Clinical trial support and other services brought in $1.6M (1%). Of every dollar of revenue, 71¢ was left as gross profit, 9¢ was left as operating profit, 14¢ was left as net earnings.

What is BillionToOne's biggest business?

Prenatal: $104M in the third quarter 2026, 85% of revenue, +41% from a year earlier.

What is BillionToOne's profit margin?

Net earnings were $17.4M, 14.1% of revenue, in the third quarter 2026; the operating margin was 9.0%.

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Updated Nov 8, 2026. Read automatically from SEC filings and public data; errors are possible. Not investment advice.