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BillionToOne (BLLN) earnings and revenue breakdown

Latest: Q3 2026 · 10-Q filed Nov 4, 2026 · BillionToOne (BLLN) Q3 2026 earnings results →

Q3 2026 Revenue up 47% year over year to $123M · 14¢ of every $1 of revenue kept as net profit · operating margin 9.0%

BillionToOne made $123M in Q3 2026 (+47% Y/Y): Prenatal $104M, Oncology $17.1M, Clinical trial support and other services $1.6M. Operating margin 9.0%, net earnings $17.4M. See where every dollar goes — costs, profit and cash — as a Sankey from the 10-Q filed Nov 4, 2026.

Revenue$123M
Year over year+47%
Operating margin9.0%
Net earnings$17.4M
Operating cash flow$12.5M

Drawing the Sankey…

Open the interactive Sankey → click any line for what the company wrote about it, compare Y/Y and Q/Q, export as PNG or PDF

What changed this quarter

Revenue was $123.0M in Q3 2026, up 47% year over year and up 12% from the previous quarter. Prenatal was the largest line at 85% of revenue. Prenatal added $30.2M year over year (up 41%), 77% of the total change.

Gross margin was 70.9%, up 0.9 points from Q3 2025. Operating profit was $11.0M, a 9.0% margin (down 2.6 points year over year). Of the extra revenue versus Q3 2025, 4% reached operating profit, below the 12% margin then. Operating expenses grew 56% against revenue growth of 47%. The fastest-growing cost line was Research & development (+56%). Net earnings were $17.4M, up 205% year over year. The effective tax rate was 0.0%. Non-operating items added $6.4M, 37% of pre-tax earnings, so the bottom line overstates operating performance.

Operating cash flow was $12.5M (up 26% year over year), 72% of net earnings. Non-cash charges added back $2.0M of depreciation and amortization and $9.7M of share-based compensation. Working capital and other items used $16.5M. After purchases of property and equipment ($3.9M), free cash flow as the company reports it was $8.6M.

Quarterly history

BillionToOne revenue by quarterBillionToOne revenue by quarter$83.5MQ3 2025$96.1MQ4 2025$108MQ1 2026$109MQ2 2026$123MQ3 2026
BillionToOne net earnings by quarterBillionToOne net earnings by quarter$5.7MQ3 2025$6.0MQ4 2025$18.0MQ1 2026$8.1MQ2 2026$17.4MQ3 2026
QuarterFormFiledRevenueY/YOp. marginNet earningsOp. cash flow
Q3 202610-QNov 4, 2026$123M+47%9.0%$17.4M$12.5M
Q2 202610-QAug 5, 2026$109M+64%5.0%$8.1M$9.1M
Q1 202610-QMay 6, 2026$108M+84%16.5%$18.0M$15.4M
Q4 202510-KMar 11, 2026$96.1M+113%10.8%$6.0M$10.8M
Q3 202510-QDec 10, 2025$83.5M+117%11.5%$5.7M$10.0M

Charts

BillionToOne: revenue growth, year over year and quarter over quarterBillionToOne: revenue growth, year over year and quarter over quarterY/YQ/Q+117%Q3 2025+113%+15%Q4 2025+84%+13%Q1 2026+64%+1%Q2 2026+47%+12%Q3 2026
Latest (Q3 2026): Y/Y +47%, Q/Q +12%.
BillionToOne: where the cash came from (+) and went (−), TTM to Q3 2026BillionToOne: where the cash came from (+) and went (−), TTM to Q3 2026Cash drawn (+) / kept (−)−$366MOther financing$289MOperating cash flow$47.9MNet borrowing (+) / repaid (−)$29.3MShares issued$14.1MCapital spending−$14.0MOther investing−$41K
From the cash-flow statement as filed (SEC XBRL). Cash is fungible: the bars do not say which dollar paid for what.
BillionToOne: profit against cash, quarter by quarterBillionToOne: profit against cash, quarter by quarterNet incomeOperating cash flow−$11.5M−$8.4MQ4 2024−$4.0M$2.6MQ1 2025−$246K$1.2MQ2 2025$5.7M$10.0MQ3 2025$6.0M$10.8MQ4 2025$18.0M$15.4MQ1 2026$8.1M$9.1MQ2 2026$17.4M$12.5MQ3 2026
Latest (Q3 2026): Net income $17.4M, Operating cash flow $12.5M.
BillionToOne: diluted shares by fiscal year (split-adjusted)BillionToOne: diluted shares by fiscal year (split-adjusted)20MFY202320MFY202421MFY2025
+8.5% since FY2023: more shares outstanding (issuance, stock pay); earlier years scaled for the 2-for-1 split before FY2025.
BillionToOne in its industry: growth against margin (22 companies, SIC 8071)BillionToOne in its industry: growth against margin (22 companies, SIC 8071)revenue growth, year over year →↑ operating marginmedian +24%median -3%LHDGXNTRAFTRERDNTGHCAILMRIVCYTCDNACSTLFLGTCFORGRALPSNLBDSXXGNAMSBGLCSERAACONBLLN (+47%, 9%)
Services-Medical Laboratories; dot size is quarterly revenue; dashed lines are the industry's medians.

Interactive views

The same charts as the app — open one to draw it.

💵Where each $1 goesinteractive

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🌏Named in Asian annual reportsinteractive

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🔄Rotation against the market and its industry (RRG)interactive

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🔍Earnings qualityinteractive

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⚖️Fair value by methodinteractive

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🔭Outlook & guidanceinteractive

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📈Investments: gains and what it boughtinteractive

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🏭Its industry’s money flow (input-output)interactive

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About BillionToOne

Unless context requires otherwise, references to “we,” “us,” “our,” “BillionToOne,” or “the Company” here refer to BillionToOne, Inc. BillionToOne is transforming healthcare by redefining molecular diagnostics. Our revolutionary single molecule next-generation sequencing (smNGS) platform achieves what was once thought impossible—detecting and precisely quantifying genetic targets with single-molecule sensitivity. At the heart of this technological breakthrough lies our patented Quantitative Counting Templates (QCTs), enabling measurements at the physical limit of detection—the single DNA molecule. This leap forward addresses a fundamental limitation in healthcare—the inability to detect sparse but clinically crucial disease signals in cell-free DNA (cfDNA).

In its own words, from its 10-K, filed Mar 11, 2026.

BillionToOne against its Services-Medical Laboratories peers

The largest companies of the same SEC industry, each at its latest quarter. Revenue growth: +47% against the peers' median +25%. Operating margin: 9.0% against the peers' median 7.0%.

CompanyQuarterRevenueY/YOp. margin
BLLN BillionToOneQ3 2026$123M+47%9.0%
LH Labcorp HoldingsQ3 2026$3.8B+7%10.6%
DGX Quest DiagnosticsQ3 2026$3.1B+10%15.5%
NTRA NateraQ3 2026$794M+34%-8.6%
FTRE Fortrea HoldingsQ3 2026$692M-1%2.2%
RDNT RadNetQ2 2026$623M+25%6.3%
GH Guardant HealthQ3 2026$361M+36%-36.8%
CAI Caris Life SciencesQ3 2026$275M+27%7.0%
LMRI Lumexa Imaging HoldingsQ2 2026$264M+5%8.7%

Source: BillionToOne 10-Q on SEC EDGAR · CIK 2070849 · Services-Medical Laboratories

Guidance and outlook

BillionToOne Revenue: guidance against what was reportedBillionToOne Revenue: guidance against what was reportedguided rangereported (above / within / below)Q4 2025$96.1MFY2025$305MFY2026
Met or beat 2 of 2 guided periods. Grey: the last range guided before the figures came out; dot: the reported figure.
BillionToOne: what its forward-looking statements are about (10-Q filed 2026-11-04)BillionToOne: what its forward-looking statements are about (10-Q filed 2026-11-04)Other7Demand7Products2Capital spending2Costs1
19 statements; tone +0.42 (−1 all cautious, +1 all confident); 1 hedged.
BillionToOne: outlook statements against the filing beforeBillionToOne: outlook statements against the filing beforeConfident8

13F: who owns BLLN and who is buying

Largest holders of BLLN (13F)Largest holders of BLLN (13F)Adams Street Partners LLC$205MPrice T Rowe Associates$121MBaillie Gifford$108MVanguard Portfolio Management LLC$101MInvesco$100MVanguard Capital Management LLC$95.9MNeuberger Berman Group LLC$91.7MBamco$89.0MWasatch Advisors LP$54.0MMillennium Management LLC$51.0M
Funds' net buying of BLLN by quarter (13F)Funds' net buying of BLLN by quarter (13F)$660M2025-12$145M2026-03−$100M2026-06
Value of shares 13F filers added minus the value they sold, each quarter (quarters with most filings in).

More on BLLN

History

Every quarter: Q3 2026 results · Q2 2026 results · Q1 2026 results · Q4 2025 results · Q3 2025 results

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