Filing Flows › BillionToOne (BLLN) › Q4 2025
BillionToOne (BLLN) Q4 2025 earnings results (fourth quarter 2025)
10-K filed Mar 11, 2026
BillionToOne (BLLN) reported revenue of $96.1M for the fourth quarter 2025 (Q4 2025), +113% from a year earlier and +15% from the quarter before. Operating margin was 10.8%, net earnings $6.0M (6.2% of revenue).
BillionToOne, Q4 2025: revenue $96.1M (+113% year over year), operating margin 10.8%, net earnings $6.0M, operating cash flow $10.8M. The chart follows the revenue to costs, profit and cash.
| Q4 2025 | Amount | Q/Q | Y/Y |
|---|---|---|---|
| Revenue | $96.1M | +15% | +113% |
| Gross profit | $68.6M | +17% | +167% |
| Operating profit | $10.3M | +7% | — |
| Net earnings | $6.0M | +5% | — |
| Operating cash flow | $10.8M | +8% | — |
| Free cash flow | $9.3M | +18% | — |
What changed
Revenue was $96.1M in Q4 2025, up 113% year over year and up 15% from the previous quarter. Prenatal was the largest line at 90% of revenue.
Gross margin was 71.4%, up 14.4 points from a year earlier. Operating profit was $10.3M, a 10.8% margin (up 36.7 points year over year). Operating expenses grew 56% against revenue growth of 113%. The fastest-growing cost line was SG&A (+67%). Net earnings were $6.0M. The effective tax rate was 5.1%.
Operating cash flow was $10.8M, 181% of net earnings. Non-cash charges added back $1.7M of depreciation and amortization and $6.3M of share-based compensation. Working capital and other items used $3.2M. Capital expenditures of $1.5M left free cash flow of $9.3M.
Questions
What was BillionToOne's revenue in the fourth quarter 2025?
BillionToOne (BLLN) reported revenue of $96.1M for the fourth quarter 2025 (Q4 2025), +113% from a year earlier and +15% from the quarter before.
Was BillionToOne profitable in the fourth quarter 2025?
Operating profit was $10.3M (10.8% of revenue) and net earnings $6.0M.
Source: BillionToOne 10-K on SEC EDGAR.