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CytomX Therapeutics (CTMX) earnings and revenue breakdown

Latest: Q3 2026 · 10-Q filed Nov 5, 2026 · CytomX Therapeutics (CTMX) Q3 2026 earnings results →

Q3 2026 Revenue down 72% year over year to $1.7M

CytomX Therapeutics made $1.7M in Q3 2026 (-72% Y/Y). Operating margin n/m, net loss $20.0M. See where every dollar goes — costs, profit and cash — as a Sankey from the 10-Q filed Nov 5, 2026.

Revenue$1.7M
Year over year-72%
Operating marginn/m
Net earnings−$20.0M
Operating cash flow$16.6M

Drawing the Sankey…

Open the interactive Sankey → click any line for what the company wrote about it, compare Y/Y and Q/Q, export as PNG or PDF

What changed this quarter

Revenue was $1.7M in Q3 2026, down 72% year over year and up 19% from the previous quarter.

Operating costs exceeded revenue by $23.5M, an operating margin of -1392.3%. Total costs grew 16% against a revenue fall of 72%. The fastest-growing cost line was General & admin (+36%). The quarter ended with a net loss of $20.0M, narrower than the previous quarter's $20.7M loss.

Operating cash flow was $16.6M. Non-cash charges added back $2.8M of share-based compensation. Working capital and other items added $33.8M. Capital expenditures of $589K left free cash flow of $16.1M.

Quarterly history

CytomX Therapeutics revenue by quarterCytomX Therapeutics revenue by quarter$50.9MQ1 2025$18.7MQ2 2025$6.0MQ3 2025$663KQ4 2025$10.3MQ1 2026$1.4MQ2 2026$1.7MQ3 2026
CytomX Therapeutics net earnings by quarterCytomX Therapeutics net earnings by quarter$23.5MQ1 2025−$154KQ2 2025−$14.2MQ3 2025−$26.5MQ4 2025−$18.2MQ1 2026−$20.7MQ2 2026−$20.0MQ3 2026
QuarterFormFiledRevenueY/YOp. marginNet earningsOp. cash flow
Q3 202610-QNov 5, 2026$1.7M-72%n/m−$20.0M$16.6M
Q2 202610-QAug 6, 2026$1.4M-92%n/m−$20.7M−$18.1M
Q1 202610-QMay 7, 2026$10.3M-80%-191.8%−$18.2M−$25.5M
Q4 202510-KMar 16, 2026$663K-98%n/m−$26.5M−$23.2M
Q3 202510-QNov 6, 2025$6.0M-82%-264.4%−$14.2M−$15.5M
Q2 202510-QAug 7, 2025$18.7M-26%-6.9%−$154K−$15.8M
Q1 202510-QMay 12, 2025$50.9M+23%44.4%$23.5M−$21.0M

Charts

CytomX Therapeutics: revenue growth, year over year and quarter over quarterCytomX Therapeutics: revenue growth, year over year and quarter over quarterY/YQ/Q+23%Q1 2025-26%-63%Q2 2025-82%-68%Q3 2025-98%-89%Q4 2025-80%+400%Q1 2026-92%-86%Q2 2026-72%+19%Q3 2026
Latest (Q3 2026): Y/Y -72%, Q/Q +19%.
CytomX Therapeutics: where the cash came from (+) and went (−), TTM to Q3 2026CytomX Therapeutics: where the cash came from (+) and went (−), TTM to Q3 2026Shares issued$246MOther investing−$200MOperating cash flow−$50.2MOther financing$5.9MCapital spending−$790KCash drawn (+) / kept (−)−$277K
From the cash-flow statement as filed (SEC XBRL). Cash is fungible: the bars do not say which dollar paid for what.
CytomX Therapeutics: profit against cash, quarter by quarterCytomX Therapeutics: profit against cash, quarter by quarterNet incomeOperating cash flow$18.9M−$19.9MQ4 2024$23.5M−$21.0MQ1 2025−$154K−$15.8MQ2 2025−$14.2M−$15.5MQ3 2025−$26.5M−$23.2MQ4 2025−$18.2M−$25.5MQ1 2026−$20.7M−$18.1MQ2 2026−$20.0M$16.6MQ3 2026
Latest (Q3 2026): Net income −$20.0M, Operating cash flow $16.6M.
CytomX Therapeutics: diluted shares by fiscal yearCytomX Therapeutics: diluted shares by fiscal year46MFY202064MFY202166MFY202274MFY202385MFY2024138MFY2025
+198.9% since FY2020: more shares outstanding (issuance, stock pay).
CytomX Therapeutics in its industry: growth against margin (225 companies, SIC 2834)CytomX Therapeutics in its industry: growth against margin (225 companies, SIC 2834)revenue growth, year over year →↑ operating marginmedian +11%median -50%JNJLLYMRKABBVPFEBMYABTREGNTEVAVTRSVRTXBHCZTSONCOGNALNYELANJAZZBMRNPRGOAMRXUTHRRPRXNRIXINSMKeenova Therapeutics plcALKSMDGLPAHCSRPTPTCTINDVBBIOACADCORTPBHANIPKNSAPTGXHRMYIONSAXSMTGTXSUPNTVTXCOLLVREOFAMPHMIRMPCRXRARELQDAARQTIRWDARDXNATRXNCREBSZLABXERSINVACRMDMNKDRYTMURGNPHATAUPHSNDXRIGLLGNDEOLSARWRPGENHROWVNDAOPKSDGRGERNETONAGIOPBYITNGXCYRXCYTKMRVIORGONUVBLFVNSIGAKROSAMRNZVRASPRYHRTXAKBABCYCKPTIGYREMGNXELTPSEPNVRDNLFCRCrinetics Pharmaceuticals, Inc.VSTMKURATBPHLABADCTNAMSFBIOXLODERMARCTRMTIAYTUFHTXENTATNXPOCULASMBWVEAPMDBFRIABEOSTOKLXRXCAPRIDYANKTRZOMDFINBPJANXSBFMGOSSETSTRCUSCPIXLIFDCUEAQSTPRAXWHWKVERUEMMAGENBVRCACELUQUREZYMEEQABCLIMNMKYNBAKTSRNACVSICNTBTRAWISCOEVFMTVRDLPCNCAMPAtaiBeckley Inc.ALMSPMHSACRSVTGNROIVKRROJAGXENSCKRSAABUSPRPHSTTKCPHITRDATXMDGOVXNWBOBIOEUPBIRDOVIDSPRBXBIOPRTAMCRBARVNMNOVSLNIGCBIOALGVNDNTHCPMDSPRORFLCOYASCYXBFRGSXTPBTAIQHCWBSERYARWRNACRGBPAVTXCLNNNTHIHINDAAGHALTONCOCRVOSKVIBOLTBDPTLYELIBOPULMCTMX (-72%, -100%)
Pharmaceutical Preparations; dot size is quarterly revenue; dashed lines are the industry's medians.

Interactive views

The same charts as the app — open one to draw it.

💵Where each $1 goesinteractive

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🌏Named in Asian annual reportsinteractive

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🔄Rotation against the market and its industry (RRG)interactive

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🔍Earnings qualityinteractive

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⚖️Fair value by methodinteractive

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🔭Outlook & guidanceinteractive

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📈Investments: gains and what it boughtinteractive

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🏭Its industry’s money flow (input-output)interactive

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About CytomX Therapeutics

We are a clinical-stage, oncology-focused biopharmaceutical company dedicated to developing innovative therapies to address major unmet need in oncology. CytomX has led the field of conditionally activated, masked biologics through the development of its PROBODY technology platform. This versatile, multi-modality platform is built on a strong foundation of tumor biology expertise, including deep knowledge of tumor-associated enzymes known as proteases. Our masking strategy is designed to reduce binding of biologic therapeutics to their targets until the mask is removed by proteases in the tumor microenvironment, providing more selective targeting of the tumor and optimizing the predicted therapeutic index of our clinical candidates.

In its own words, from its 10-K, filed Mar 16, 2026.

CytomX Therapeutics against its Pharmaceutical Preparations peers

The largest companies of the same SEC industry, each at its latest quarter. Revenue growth: -72% against the peers' median +7%.

CompanyQuarterRevenueY/YOp. margin
CTMX CytomX TherapeuticsQ3 2026$1.7M-72%n/m
JNJ Johnson & JohnsonQ3 2026$25.4B+6%0.1%
LLY ELI LillyQ3 2026$24.4B+39%34.5%
MRK MerckQ3 2026$18.1B+5%30.7%
ABBV AbbVieQ3 2026$17.4B+10%36.0%
PFE PfizerQ3 2026$16.6B-0.4%20.4%
BMY Bristol Myers SquibbQ3 2026$13.1B+7%19.4%
ABT Abbott LaboratoriesQ3 2026$13.0B+14%10.4%
REGN Regeneron PharmaceuticalsQ3 2026$5.1B+36%40.0%

Source: CytomX Therapeutics 10-Q on SEC EDGAR · CIK 1501989 · Pharmaceutical Preparations

Guidance and outlook

CytomX Therapeutics: what its forward-looking statements are about (10-Q filed 2026-11-05)CytomX Therapeutics: what its forward-looking statements are about (10-Q filed 2026-11-05)Other11Demand7Costs2
20 statements; tone +0.05 (−1 all cautious, +1 all confident); 5 hedged.
CytomX Therapeutics: outlook statements against the filing beforeCytomX Therapeutics: outlook statements against the filing beforeConfident4Cautious3

13F: who owns CTMX and who is buying

Largest holders of CTMX (13F)Largest holders of CTMX (13F)FMR LLC$123MKynam Capital Management, LP$81.4MBlackRock$65.8MBank of America$56.6MState Street$44.1MPerceptive Advisors LLC$39.1MVanguard Group$36.1MVanguard Capital Management LLC$32.0MPoint72 Asset Management, L.P.$29.3MWellington Management Group LLP$19.4M
Funds' net buying of CTMX by quarter (13F)Funds' net buying of CTMX by quarter (13F)$1.5M2024-09−$576K2024-12−$404K2025-03$201M2025-06$12.0M2025-09$24.2M2025-12$217M2026-03$74.2M2026-06
Value of shares 13F filers added minus the value they sold, each quarter (quarters with most filings in).

More on CTMX

History

Every quarter: Q3 2026 results · Q2 2026 results · Q1 2026 results · Q4 2025 results · Q3 2025 results · Q2 2025 results · Q1 2025 results

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