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CytomX Therapeutics (CTMX) Q2 2025 earnings results (second quarter 2025)

10-Q filed Aug 7, 2025

CytomX Therapeutics (CTMX) reported revenue of $18.7M for the second quarter 2025 (Q2 2025), -26% from a year earlier and -63% from the quarter before. Operating margin was -6.9%, net loss $154K (0.8% of revenue).

Revenue$18.7M
Year over year-26%
Quarter over quarter-63%
Operating margin-6.9%
Net earnings−$154K

CytomX Therapeutics, Q2 2025: revenue $18.7M (-26% year over year), operating margin -6.9%, net loss $154K, operating cash flow −$15.8M. The chart follows the revenue to costs, profit and cash.

Q2 2025AmountQ/QY/Y
Revenue$18.7M-63%-26%
Operating profit−$1.3M-106%—
Net earnings−$154K-101%—
Operating cash flow−$15.8M——

What changed

Revenue was $18.7M in Q2 2025, down 26% year over year and down 63% from the previous quarter.

Operating costs exceeded revenue by $1.3M, an operating margin of -6.9%. Total costs fell 41% while revenue fell 26%. The quarter ended with a net loss of $154K, after a profit of $23.5M the previous quarter. Non-operating items added $1.2M, -1313% of pre-tax earnings, so the bottom line overstates operating performance.

Operating cash flow was −$15.8M. Non-cash charges added back $1.4M of share-based compensation. Working capital and other items used $17.0M. Capital expenditures of $27K exceeded it, leaving free cash flow of −$15.8M.

Questions

What was CytomX Therapeutics' revenue in the second quarter 2025?

CytomX Therapeutics (CTMX) reported revenue of $18.7M for the second quarter 2025 (Q2 2025), -26% from a year earlier and -63% from the quarter before.

Was CytomX Therapeutics profitable in the second quarter 2025?

Operating loss was $1.3M (-6.9% of revenue) and net loss $154K.

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Source: CytomX Therapeutics 10-Q on SEC EDGAR.