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Dianthus Therapeutics (DNTH) Q4 2025 earnings results (fourth quarter 2025)

10-K filed Mar 9, 2026

Dianthus Therapeutics (DNTH) reported revenue of $284K for the fourth quarter 2025 (Q4 2025), -79% from a year earlier and -28% from the quarter before.

Revenue$284K
Year over year-79%
Quarter over quarter-28%
Operating margin—
Net earnings−$64.4M

Dianthus Therapeutics, Q4 2025: revenue $284K (-79% year over year), net loss $64.4M, operating cash flow −$47.0M. The chart follows the revenue to costs, profit and cash.

Q4 2025AmountQ/QY/Y
Revenue$284K-28%-79%
Operating profit−$69.5M——
Net earnings−$64.4M——
Operating cash flow−$47.0M——

What changed

Revenue was $284K in Q4 2025, down 79% year over year and down 28% from the previous quarter.

Operating costs exceeded revenue by $69.5M, an operating margin of -24486.3%. Total costs grew 110% against a revenue fall of 79%. The fastest-growing cost line was Research & development (+127%). The quarter ended with a net loss of $64.4M, wider than the previous quarter's $36.8M loss.

Operating cash flow was −$47.0M. Non-cash charges added back $27K of depreciation and $6.0M of share-based compensation. Working capital and other items added $11.4M. Capital expenditures of $138K exceeded it, leaving free cash flow of −$47.1M.

Questions

What was Dianthus Therapeutics' revenue in the fourth quarter 2025?

Dianthus Therapeutics (DNTH) reported revenue of $284K for the fourth quarter 2025 (Q4 2025), -79% from a year earlier and -28% from the quarter before.

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Source: Dianthus Therapeutics 10-K on SEC EDGAR.