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Ensysce Biosciences (ENSC) Q3 2025 earnings results (third quarter 2025)

10-Q filed Nov 14, 2025

Ensysce Biosciences (ENSC) reported revenue of $493K for the third quarter 2025 (Q3 2025), -86% from a year earlier and -64% from the quarter before. Operating margin was -758.7%, net loss $3.7M (756.3% of revenue).

Revenue$493K
Year over year-86%
Quarter over quarter-64%
Operating margin-758.7%
Net earnings−$3.7M

Ensysce Biosciences, Q3 2025: revenue $493K (-86% year over year), operating margin -758.7%, net loss $3.7M, operating cash flow −$1.9M. The chart follows the revenue to costs, profit and cash.

Q3 2025AmountQ/QY/Y
Revenue$493K-64%-86%
Operating profit−$3.7M——
Net earnings−$3.7M——
Operating cash flow−$1.9M——

What changed

Revenue was $493K in Q3 2025, down 86% year over year and down 64% from the previous quarter.

Operating costs exceeded revenue by $3.7M, an operating margin of -758.7%. Total costs grew 53% against a revenue fall of 86%. The fastest-growing cost line was Research & development (+75%). The quarter ended with a net loss of $3.7M, wider than the previous quarter's $1.7M loss.

Operating cash flow was −$1.9M. Non-cash charges added back $46K of share-based compensation. Working capital and other items added $1.8M.

Questions

What was Ensysce Biosciences' revenue in the third quarter 2025?

Ensysce Biosciences (ENSC) reported revenue of $493K for the third quarter 2025 (Q3 2025), -86% from a year earlier and -64% from the quarter before.

Was Ensysce Biosciences profitable in the third quarter 2025?

Operating loss was $3.7M (-758.7% of revenue) and net loss $3.7M.

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Source: Ensysce Biosciences 10-Q on SEC EDGAR.