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Humacyte (HUMA) Q4 2025 earnings results (fourth quarter 2025)

10-K filed Mar 27, 2026

Humacyte (HUMA) reported revenue of $467K for the fourth quarter 2025 (Q4 2025) and -38% from the quarter before.

Revenue$467K
Year over year—
Quarter over quarter-38%
Operating margin—
Net earnings−$24.8M

Humacyte, Q4 2025: revenue $467K, net loss $24.8M, operating cash flow −$26.1M. The chart follows the revenue to costs, profit and cash.

Q4 2025AmountQ/QY/Y
Revenue$467K-38%—
Operating profit−$30.8M——
Net earnings−$24.8M——
Operating cash flow−$26.1M——

What changed

Revenue was $467K in Q4 2025, down 38% from the previous quarter.

Operating costs exceeded revenue by $30.8M, an operating margin of -6603.0%. The quarter ended with a net loss of $24.8M, wider than the previous quarter's $17.5M loss. Non-operating items added $6.0M, -24% of pre-tax earnings, so the bottom line overstates operating performance.

Operating cash flow was −$26.1M. Non-cash charges added back $1.3M of depreciation and $2.5M of share-based compensation. Working capital and other items used $5.1M. Capital expenditures of $39K exceeded it, leaving free cash flow of −$26.2M.

Questions

What was Humacyte's revenue in the fourth quarter 2025?

Humacyte (HUMA) reported revenue of $467K for the fourth quarter 2025 (Q4 2025) and -38% from the quarter before.

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Source: Humacyte 10-K on SEC EDGAR.