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Illumina (ILMN) Q3 2025 earnings results (third quarter 2025)

10-Q filed Oct 31, 2025

Illumina (ILMN) reported revenue of $1.1B for the third quarter 2025 (Q3 2025), +0.4% from a year earlier and +2% from the quarter before. Operating margin was 20.9%, net earnings $150M (13.8% of revenue).

Revenue$1.1B
Year over year+0.4%
Quarter over quarter+2%
Operating margin20.9%
Net earnings$150M

Illumina, Q3 2025: revenue $1.1B (+0.4% year over year), operating margin 20.9%, net earnings $150M, operating cash flow $284M. The chart follows the revenue to costs, profit and cash.

Q3 2025AmountQ/QY/Y
Revenue$1.1B+2%+0.4%
Gross profit$733M+5%-2%
Operating profit$227M+6%-69%
Net earnings$150M-36%-79%
Operating cash flow$284M+21%-10%
Free cash flow$253M—-11%

What changed

Revenue was $1.1B in Q3 2025, roughly flat year over year and up 2% from the previous quarter. Consumables was the largest line at 75% of revenue. Consumables added $0.01B year over year (up 1%), 225% of the total change. Service declined 5%.

Gross margin was 67.6%, down 1.4 points from a year earlier. Operating profit was $0.23B, a 20.9% margin (down 47.7 points year over year). Operating profit fell $0.51B even though revenue rose $4.0M versus a year earlier, so costs grew faster than sales. Operating expenses grew 12550% against flat revenue. Net earnings were $0.15B, down 79% year over year. The effective tax rate was 31.8%.

Operating cash flow was $0.28B (down 10% year over year), 189% of net earnings. Non-cash charges added back $0.07B of depreciation and amortization and $0.07B of share-based compensation. After purchases of property and equipment ($0.03B), free cash flow as the company reports it was $0.25B.

Questions

What was Illumina's revenue in the third quarter 2025?

Illumina (ILMN) reported revenue of $1.1B for the third quarter 2025 (Q3 2025), +0.4% from a year earlier and +2% from the quarter before.

Was Illumina profitable in the third quarter 2025?

Operating profit was $227M (20.9% of revenue) and net earnings $150M.

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Source: Illumina 10-Q on SEC EDGAR.