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Insmed (INSM) Q1 2026 earnings results (first quarter 2026)

10-Q filed May 7, 2026

Insmed (INSM) reported revenue of $306M for the first quarter 2026 (Q1 2026), +230% from a year earlier and +16% from the quarter before. Operating margin was -50.1%, net loss $164M (53.5% of revenue).

Revenue$306M
Year over year+230%
Quarter over quarter+16%
Operating margin-50.1%
Net earnings−$164M

Insmed, Q1 2026: revenue $306M (+230% year over year), operating margin -50.1%, net loss $164M, operating cash flow −$223M. The chart follows the revenue to costs, profit and cash.

Q1 2026AmountQ/QY/Y
Revenue$306M+16%+230%
Operating profit−$153M——
Net earnings−$164M——
Operating cash flow−$223M——

What changed

Revenue was $306.0M in Q1 2026, up 230% year over year and up 16% from the previous quarter. BRINSUPRI was the largest line at 68% of revenue. ARIKAYCE added $5.3M year over year (up 6%), 2% of the total change.

Operating costs exceeded revenue by $153.3M, an operating margin of -50.1%. Total costs grew 35% against revenue growth of 230%. The quarter ended with a net loss of $163.6M, narrower than the previous quarter's $328.5M loss.

Operating cash flow was −$222.7M. Non-cash charges added back $5.0M of depreciation and amortization and $45.8M of share-based compensation. Working capital and other items used $109.9M. Capital expenditures of $3.5M exceeded it, leaving free cash flow of −$226.2M.

Questions

What was Insmed's revenue in the first quarter 2026?

Insmed (INSM) reported revenue of $306M for the first quarter 2026 (Q1 2026), +230% from a year earlier and +16% from the quarter before.

Was Insmed profitable in the first quarter 2026?

Operating loss was $153M (-50.1% of revenue) and net loss $164M.

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Source: Insmed 10-Q on SEC EDGAR.