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Insmed (INSM) earnings and revenue breakdown

Latest: Q3 2026 · 10-Q filed Oct 29, 2026 · Insmed (INSM) Q3 2026 earnings results →

Q3 2026 Revenue up 268% year over year to $524M · 19¢ of every $1 of revenue lost · operating margin -17.0%

Insmed made $524M in Q3 2026 (+268% Y/Y): BRINSUPRI $400M, ARIKAYCE $124M. Operating margin -17.0%, net loss $100M. See where every dollar goes — costs, profit and cash — as a Sankey from the 10-Q filed Oct 29, 2026.

Revenue$524M
Year over year+268%
Operating margin-17.0%
Net earnings−$100M
Operating cash flow−$36.5M

Drawing the Sankey…

Open the interactive Sankey → click any line for what the company wrote about it, compare Y/Y and Q/Q, export as PNG or PDF

What changed this quarter

Revenue was $524.4M in Q3 2026, up 268% year over year and up 23% from the previous quarter. BRINSUPRI was the largest line at 76% of revenue. BRINSUPRI added $372.0M year over year (up 1326%), 97% of the total change.

Operating costs exceeded revenue by $89.4M, an operating margin of -17.0%. Total costs grew 21% against revenue growth of 268%. The fastest-growing cost line was Cost of revenue (+166%). The quarter ended with a net loss of $100.3M, wider than the previous quarter's $13.2M loss.

Operating cash flow was −$36.5M. Non-cash charges added back $8.4M of depreciation and amortization and $41.2M of share-based compensation. Working capital and other items added $14.2M. Capital expenditures of $5.6M exceeded it, leaving free cash flow of −$42.1M.

Quarterly history

Insmed revenue by quarterInsmed revenue by quarter$92.8MQ1 2025$107MQ2 2025$142MQ3 2025$264MQ4 2025$306MQ1 2026$425MQ2 2026$524MQ3 2026
Insmed net earnings by quarterInsmed net earnings by quarter−$257MQ1 2025−$322MQ2 2025−$370MQ3 2025−$328MQ4 2025−$164MQ1 2026−$13.2MQ2 2026−$100MQ3 2026
QuarterFormFiledRevenueY/YOp. marginNet earningsOp. cash flow
Q3 202610-QOct 29, 2026$524M+268%-17.0%−$100M−$36.5M
Q2 202610-QAug 6, 2026$425M+296%-0.4%−$13.2M−$88.8M
Q1 202610-QMay 7, 2026$306M+230%-50.1%−$164M−$223M
Q4 202510-KFeb 19, 2026$264M+153%-121.2%−$328M−$248M
Q3 202510-QOct 30, 2025$142M+52%-257.1%−$370M−$220M
Q2 202510-QAug 7, 2025$107M+19%-291.3%−$322M−$206M
Q1 202510-QMay 8, 2025$92.8M+23%-267.3%−$257M−$262M

Charts

Insmed: revenue growth, year over year and quarter over quarterInsmed: revenue growth, year over year and quarter over quarterY/YQ/Q+23%Q1 2025+19%+16%Q2 2025+52%+33%Q3 2025+153%+85%Q4 2025+230%+16%Q1 2026+296%+39%Q2 2026+268%+23%Q3 2026
Latest (Q3 2026): Y/Y +268%, Q/Q +23%.
Insmed: where the cash came from (+) and went (−), TTM to Q3 2026Insmed: where the cash came from (+) and went (−), TTM to Q3 2026Operating cash flow−$596MOther investing$576MShares issued$117MCash drawn (+) / kept (−)−$61.8MCapital spending−$32.0MNet borrowing (+) / repaid (−)−$3.2MExchange rates−$564K
From the cash-flow statement as filed (SEC XBRL). Cash is fungible: the bars do not say which dollar paid for what.
Insmed: profit against cash, quarter by quarterInsmed: profit against cash, quarter by quarterNet incomeOperating cash flow−$236M−$196MQ4 2024−$257M−$262MQ1 2025−$322M−$206MQ2 2025−$370M−$220MQ3 2025−$328M−$248MQ4 2025−$164M−$223MQ1 2026−$13.2M−$88.8MQ2 2026−$100M−$36.5MQ3 2026
Latest (Q3 2026): Net income −$100M, Operating cash flow −$36.5M.
Insmed: diluted shares by fiscal yearInsmed: diluted shares by fiscal year98MFY2020112MFY2021123MFY2022140MFY2023164MFY2024199MFY2025
+103.9% since FY2020: more shares outstanding (issuance, stock pay).
Insmed: long-term debt falling due (FY2025)Insmed: long-term debt falling due (FY2025)$342M2028$205M2029
Cash $510M, short-term investments $920M, long-term debt $547M at 2025-12-31.
Insmed in its industry: growth against margin (225 companies, SIC 2834)Insmed in its industry: growth against margin (225 companies, SIC 2834)revenue growth, year over year →↑ operating marginmedian +11%median -50%JNJLLYMRKABBVPFEBMYABTREGNTEVAVTRSVRTXBHCZTSONCOGNALNYELANJAZZBMRNPRGOAMRXUTHRRPRXNRIXKeenova Therapeutics plcALKSMDGLPAHCSRPTPTCTINDVBBIOACADCORTPBHANIPKNSAPTGXHRMYIONSAXSMTGTXSUPNTVTXCOLLVREOFAMPHMIRMPCRXRARELQDAARQTIRWDARDXNATRXNCREBSZLABXERSINVACRMDMNKDRYTMURGNPHATAUPHSNDXRIGLLGNDEOLSARWRPGENHROWVNDAOPKSDGRGERNETONAGIOPBYITNGXCYRXCYTKMRVIORGONUVBLFVNSIGAKROSAMRNZVRASPRYHRTXAKBABCYCKPTIGYREMGNXELTPSEPNVRDNLFCRCrinetics Pharmaceuticals, Inc.VSTMKURATBPHLABADCTNAMSFBIOXLODERMARCTRMTIAYTUFHTXENTATNXPOCULASMBWVEAPMDBFRIABEOSTOKLXRXCAPRIDYANKTRZOMDFINBPJANXSBFMGOSSETSTRCUSCPIXLIFDCUEAQSTPRAXWHWKVERUEMMAGENBVRCACELUQUREZYMEEQABCLIMNMKYNBAKTSRNACVSICNTBTRAWISCOEVFMTVRDLPCNCAMPAtaiBeckley Inc.CTMXALMSPMHSACRSVTGNROIVKRROJAGXENSCKRSAABUSPRPHSTTKCPHITRDATXMDGOVXNWBOBIOEUPBIRDOVIDSPRBXBIOPRTAMCRBARVNMNOVSLNIGCBIOALGVNDNTHCPMDSPRORFLCOYASCYXBFRGSXTPBTAIQHCWBSERYARWRNACRGBPAVTXCLNNNTHIHINDAAGHALTONCOCRVOSKVIBOLTBDPTLYELIBOPULMINSM (+268%, -17%)
Pharmaceutical Preparations; dot size is quarterly revenue; dashed lines are the industry's medians.

Interactive views

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💵Where each $1 goesinteractive

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🌏Named in Asian annual reportsinteractive

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🔄Rotation against the market and its industry (RRG)interactive

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🔍Earnings qualityinteractive

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⚖️Fair value by methodinteractive

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🔭Outlook & guidanceinteractive

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📈Investments: gains and what it boughtinteractive

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🏭Its industry’s money flow (input-output)interactive

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About Insmed

We are a people-first global biopharmaceutical company striving to deliver first- and best-in-class therapies to transform the lives of patients facing serious diseases. Our commercial portfolio and clinical pipeline are organized around three therapeutic areas: Respiratory, Immunology & Inflammation, and Neuro & Other Rare. To complement our internal research and development, we also actively evaluate in-licensing and acquisition opportunities for commercial products, product candidates and technologies. Our two commercial products, ARIKAYCE ® and BRINSUPRI ® , are both part of the Respiratory therapeutic area. ARIKAYCE is approved in the US as ARIKAYCE (amikacin liposome inhalation suspension), in Europe as ARIKAYCE Liposomal 590 mg Nebuliser Dispersion and in Japan as ARIKAYCE inhalation 590mg (amikacin sulfate inhalation drug product).

In its own words, from its 10-K, filed Feb 19, 2026.

Insmed against its Pharmaceutical Preparations peers

The largest companies of the same SEC industry, each at its latest quarter. Revenue growth: +268% against the peers' median +10%. Operating margin: -17.0% against the peers' median 20.4%.

CompanyQuarterRevenueY/YOp. margin
INSM InsmedQ3 2026$524M+268%-17.0%
JNJ Johnson & JohnsonQ3 2026$25.4B+6%0.1%
LLY ELI LillyQ3 2026$24.4B+39%34.5%
MRK MerckQ3 2026$18.1B+5%30.7%
ABBV AbbVieQ3 2026$17.4B+10%36.0%
PFE PfizerQ3 2026$16.6B-0.4%20.4%
BMY Bristol Myers SquibbQ3 2026$13.1B+7%19.4%
ABT Abbott LaboratoriesQ3 2026$13.0B+14%10.4%
REGN Regeneron PharmaceuticalsQ3 2026$5.1B+36%40.0%

Source: Insmed 10-Q on SEC EDGAR · CIK 1104506 · Pharmaceutical Preparations

13F: who owns INSM and who is buying

Largest holders of INSM (13F)Largest holders of INSM (13F)Vanguard Group$3.7BFMR LLC$1.7BBlackRock$1.7BVanguard Portfolio Management LLC$1.1BVanguard Capital Management LLC$1.0BBaker Bros. Advisors LP$938MCapital International Investors$878MDarwin Global Management$674MAmeriprise Financial$659MOrbis Allan Gray$648M
Funds' net buying of INSM by quarter (13F)Funds' net buying of INSM by quarter (13F)$284M2024-09$11.7M2024-12$299M2025-03$40.1M2025-06−$517M2025-09$421M2025-12$725M2026-03$1.1B2026-06
Value of shares 13F filers added minus the value they sold, each quarter (quarters with most filings in).

More on INSM

History

Every quarter: Q3 2026 results · Q2 2026 results · Q1 2026 results · Q4 2025 results · Q3 2025 results · Q2 2025 results · Q1 2025 results

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