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Insmed (INSM) Q2 2025 earnings results (second quarter 2025)

10-Q filed Aug 7, 2025

Insmed (INSM) reported revenue of $107M for the second quarter 2025 (Q2 2025), +19% from a year earlier and +16% from the quarter before. Operating margin was -291.3%, net loss $322M (299.5% of revenue).

Revenue$107M
Year over year+19%
Quarter over quarter+16%
Operating margin-291.3%
Net earnings−$322M

Insmed, Q2 2025: revenue $107M (+19% year over year), operating margin -291.3%, net loss $322M, operating cash flow −$206M. The chart follows the revenue to costs, profit and cash.

Q2 2025AmountQ/QY/Y
Revenue$107M+16%+19%
Operating profit−$313M——
Net earnings−$322M——
Operating cash flow−$206M——

What changed

Revenue was $107.4M in Q2 2025, up 19% year over year and up 16% from the previous quarter.

Operating costs exceeded revenue by $312.9M, an operating margin of -291.3%. Total costs grew 11% against revenue growth of 19%. The fastest-growing cost line was SG&A (+45%). The quarter ended with a net loss of $321.7M, wider than the previous quarter's $256.6M loss.

Operating cash flow was −$205.6M. Non-cash charges added back $3.7M of depreciation and amortization and $43.0M of share-based compensation. Working capital and other items added $69.4M. Capital expenditures of $3.5M exceeded it, leaving free cash flow of −$209.1M.

Questions

What was Insmed's revenue in the second quarter 2025?

Insmed (INSM) reported revenue of $107M for the second quarter 2025 (Q2 2025), +19% from a year earlier and +16% from the quarter before.

Was Insmed profitable in the second quarter 2025?

Operating loss was $313M (-291.3% of revenue) and net loss $322M.

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Source: Insmed 10-Q on SEC EDGAR.