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Krystal Biotech (KRYS) Q3 2025 earnings results (third quarter 2025)

10-Q filed Nov 3, 2025

Krystal Biotech (KRYS) reported revenue of $97.8M for the third quarter 2025 (Q3 2025), +17% from a year earlier and +2% from the quarter before. Operating margin was 42.3%, net earnings $79.4M (81.2% of revenue).

Revenue$97.8M
Year over year+17%
Quarter over quarter+2%
Operating margin42.3%
Net earnings$79.4M

Krystal Biotech, Q3 2025: revenue $97.8M (+17% year over year), operating margin 42.3%, net earnings $79.4M, operating cash flow $39.7M. The chart follows the revenue to costs, profit and cash.

Q3 2025AmountQ/QY/Y
Revenue$97.8M+2%+17%
Operating profit$41.4M+5%+84%
Net earnings$79.4M+107%+192%
Operating cash flow$39.7M-25%-33%
Free cash flow$38.0M-25%-34%

What changed

Revenue was $97.8M in Q3 2025, up 17% year over year and up 2% from the previous quarter.

Operating profit was $41.4M, a 42.3% margin (up 15.5 points year over year). Of the extra revenue versus a year earlier, 135% reached operating profit, above the 27% margin then. Total costs fell 8% while revenue rose 17%. The fastest-growing cost line was SG&A (+31%). Net earnings were $79.4M, up 192% year over year. The effective tax rate was -65.5%.

Operating cash flow was $39.7M (down 33% year over year), 50% of net earnings. Non-cash charges added back $1.4M of depreciation and $13.2M of share-based compensation. Working capital and other items used $54.3M. Capital expenditures of $1.7M left free cash flow of $38.0M.

Questions

What was Krystal Biotech's revenue in the third quarter 2025?

Krystal Biotech (KRYS) reported revenue of $97.8M for the third quarter 2025 (Q3 2025), +17% from a year earlier and +2% from the quarter before.

Was Krystal Biotech profitable in the third quarter 2025?

Operating profit was $41.4M (42.3% of revenue) and net earnings $79.4M.

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Source: Krystal Biotech 10-Q on SEC EDGAR.