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Krystal Biotech (KRYS) earnings and revenue breakdown

Latest: Q3 2026 · 10-Q filed Nov 2, 2026 · Krystal Biotech (KRYS) Q3 2026 earnings results →

Q3 2026 Revenue up 30% year over year to $127M · 50¢ of every $1 of revenue kept as net profit · operating margin 55.9%

Krystal Biotech made $127M in Q3 2026 (+30% Y/Y). Operating margin 55.9%, net earnings $63.1M. See where every dollar goes — costs, profit and cash — as a Sankey from the 10-Q filed Nov 2, 2026.

Revenue$127M
Year over year+30%
Operating margin55.9%
Net earnings$63.1M
Operating cash flow$91.2M

Drawing the Sankey…

Open the interactive Sankey → click any line for what the company wrote about it, compare Y/Y and Q/Q, export as PNG or PDF

What changed this quarter

Revenue was $127.3M in Q3 2026, up 30% year over year and up 7% from the previous quarter.

Operating profit was $71.1M, a 55.9% margin (up 13.6 points year over year). Of the extra revenue versus Q3 2025, 101% reached operating profit, above the 42% margin then. Total costs fell 0% while revenue rose 30%. The fastest-growing cost line was Other operating costs (+77%). Net earnings were $63.1M, down 21% year over year. The effective tax rate was 21.3%.

Operating cash flow was $91.2M (up 130% year over year), 145% of net earnings. Non-cash charges added back $1.5M of depreciation and $13.9M of share-based compensation. Working capital and other items added $12.7M. Capital expenditures of $1.0M left free cash flow of $90.3M.

Quarterly history

Krystal Biotech revenue by quarterKrystal Biotech revenue by quarter$88.2MQ1 2025$96.0MQ2 2025$97.8MQ3 2025$107MQ4 2025$116MQ1 2026$119MQ2 2026$127MQ3 2026
Krystal Biotech net earnings by quarterKrystal Biotech net earnings by quarter$35.7MQ1 2025$38.3MQ2 2025$79.4MQ3 2025$51.4MQ4 2025$55.9MQ1 2026$54.8MQ2 2026$63.1MQ3 2026
QuarterFormFiledRevenueY/YOp. marginNet earningsOp. cash flow
Q3 202610-QNov 2, 2026$127M+30%55.9%$63.1M$91.2M
Q2 202610-QAug 3, 2026$119M+24%49.0%$54.8M$74.8M
Q1 202610-QMay 4, 2026$116M+32%46.1%$55.9M$80.4M
Q4 202510-KFeb 17, 2026$107M+18%41.3%$51.4M$77.5M
Q3 202510-QNov 3, 2025$97.8M+17%42.3%$79.4M$39.7M
Q2 202510-QAug 4, 2025$96.0M+37%41.0%$38.3M$52.7M
Q1 202510-QMay 6, 2025$88.2M+95%41.1%$35.7M$31.0M

Charts

Krystal Biotech: revenue growth, year over year and quarter over quarterKrystal Biotech: revenue growth, year over year and quarter over quarterY/YQ/Q+95%Q1 2025+37%+9%Q2 2025+17%+2%Q3 2025+18%+10%Q4 2025+32%+9%Q1 2026+24%+2%Q2 2026+30%+7%Q3 2026
Latest (Q3 2026): Y/Y +30%, Q/Q +7%.
Krystal Biotech: where the cash came from (+) and went (−), TTM to Q3 2026Krystal Biotech: where the cash came from (+) and went (−), TTM to Q3 2026Operating cash flow$324MOther investing−$258MCash drawn (+) / kept (−)−$70.2MShares issued$40.8MOther financing−$17.1MCapital spending−$13.8MExchange rates−$5.4M
From the cash-flow statement as filed (SEC XBRL). Cash is fungible: the bars do not say which dollar paid for what.
Krystal Biotech: profit against cash, quarter by quarterKrystal Biotech: profit against cash, quarter by quarterNet incomeOperating cash flow$45.5M$52.8MQ4 2024$35.7M$31.0MQ1 2025$38.3M$52.7MQ2 2025$79.4M$39.7MQ3 2025$51.4M$77.5MQ4 2025$55.9M$80.4MQ1 2026$54.8M$74.8MQ2 2026$63.1M$91.2MQ3 2026
Latest (Q3 2026): Net income $63.1M, Operating cash flow $91.2M.
Krystal Biotech: diluted shares by fiscal yearKrystal Biotech: diluted shares by fiscal year19MFY202022MFY202125MFY202228MFY202330MFY202430MFY2025
+59.4% since FY2020: more shares outstanding (issuance, stock pay).
Krystal Biotech in its industry: growth against margin (76 companies, SIC 2836)Krystal Biotech in its industry: growth against margin (76 companies, SIC 2836)revenue growth, year over year →↑ operating marginmedian +9%median -100%AMGNGILDBIIBMRNANBIXEXELHALOMGTXTECHVIRRGENTARSBCRXALECADMAIOVATWSTIPSCIMCRVISKVCELADPTNVAXKYMRGLUEIBRXAUTLAGENDNAPLXRXRXFENCCSBRCHRSIVVDCRSPEDITDTILVXRTSTRORGNXCCCCBSEMSCLXACOGTSHASRZNVYGRFDMTLENZALGSXFORELUTFATEOCGNSCTXCRBUCGONDBVTINBXMGXLCTXTCRXDYAIPRMEATRAVitro Biopharma, Inc.HUMARLAYPLURBEAMPROKCRDFAIMVIVSKRYS (+30%, 56%)
Biological Products, (No Diagnostic Substances); dot size is quarterly revenue; dashed lines are the industry's medians.

Interactive views

The same charts as the app — open one to draw it.

💵Where each $1 goesinteractive

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🌏Named in Asian annual reportsinteractive

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🔄Rotation against the market and its industry (RRG)interactive

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🔍Earnings qualityinteractive

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⚖️Fair value by methodinteractive

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🔭Outlook & guidanceinteractive

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📈Investments: gains and what it boughtinteractive

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🏭Its industry’s money flow (input-output)interactive

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About Krystal Biotech

We are a fully integrated, global, commercial-stage biotechnology company focused on the discovery, development, manufacturing and commercialization of genetic medicines to treat diseases with high unmet medical needs. Using our patented gene therapy technology platform that is based on engineered herpes simplex virus-1 (“HSV-1”), we create vectors that efficiently deliver therapeutic transgenes to cells of interest in multiple organ systems. The cell’s own machinery then transcribes and translates the transgene to treat the disease. Our vectors are amenable to formulation for non-invasive or minimally invasive routes of administration at a healthcare professional’s office or in the patient’s home by a healthcare professional, caregiver, or directly by the patient themselves.

In its own words, from its 10-K, filed Feb 17, 2026.

Krystal Biotech against its Biological Products, (No Diagnostic Substances) peers

The largest companies of the same SEC industry, each at its latest quarter. Revenue growth: +30% against the peers' median +29%. Operating margin: 55.9% against the peers' median 40.8%.

CompanyQuarterRevenueY/YOp. margin
KRYS Krystal BiotechQ3 2026$127M+30%55.9%
AMGN AmgenQ3 2026$10.4B+8%35.8%
GILD Gilead SciencesQ3 2026$8.3B+7%41.7%
BIIB BiogenQ3 2026$2.8B+11%-0.3%
MRNA ModernaQ3 2026$1.3B+29%9.9%
NBIX Neurocrine BiosciencesQ3 2026$1.1B+41%29.5%
EXEL ExelixisQ3 2026$659M+10%40.8%
HALO Halozyme TherapeuticsQ3 2026$493M+39%59.8%
MGTX MeiraGTx HoldingsQ2 2026$321M87×76.0%

Source: Krystal Biotech 10-Q on SEC EDGAR · CIK 1711279 · Biological Products, (No Diagnostic Substances)

Guidance and outlook

Krystal Biotech: what its forward-looking statements are about (10-Q filed 2026-11-02)Krystal Biotech: what its forward-looking statements are about (10-Q filed 2026-11-02)Other12Costs7Demand4Products4Margins2Legal & regulation1Supply chain1
31 statements; tone +0.16 (−1 all cautious, +1 all confident); 6 hedged.
Krystal Biotech: outlook statements against the filing beforeKrystal Biotech: outlook statements against the filing beforeConfident7Cautious2

13F: who owns KRYS and who is buying

Largest holders of KRYS (13F)Largest holders of KRYS (13F)FMR LLC$1.6BBlackRock$1.6BAvoro Capital Advisors LLC$1.1BVanguard Group$685MVanguard Portfolio Management LLC$585MState Street$502MVanguard Capital Management LLC$461MSoleus Capital Management, L.P.$349MCapital World Investors$289MGeode Capital Management, LLC$260M
Funds' net buying of KRYS by quarter (13F)Funds' net buying of KRYS by quarter (13F)−$17.2M2024-09−$42.4M2024-12−$29.6M2025-03−$31.4M2025-06$156M2025-09$96.5M2025-12$49.9M2026-03$398M2026-06
Value of shares 13F filers added minus the value they sold, each quarter (quarters with most filings in).

More on KRYS

History

Every quarter: Q3 2026 results · Q2 2026 results · Q1 2026 results · Q4 2025 results · Q3 2025 results · Q2 2025 results · Q1 2025 results

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