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Exelixis (EXEL) earnings and revenue breakdown

Latest: Q3 2026 · 10-Q filed Oct 29, 2026 · Exelixis (EXEL) Q3 2026 earnings results →

Q3 2026 Revenue up 10% year over year to $659M · 33¢ of every $1 of revenue kept as net profit · operating margin 40.8%

Exelixis made $659M in Q3 2026 (+10% Y/Y): Net product revenues $605M, Collaboration $53.8M, COMETRIQ $1.8M. Operating margin 40.8%, net earnings $218M. See where every dollar goes — costs, profit and cash — as a Sankey from the 10-Q filed Oct 29, 2026.

Revenue$659M
Year over year+10%
Operating margin40.8%
Net earnings$218M
Operating cash flow$280M

Drawing the Sankey…

Open the interactive Sankey → click any line for what the company wrote about it, compare Y/Y and Q/Q, export as PNG or PDF

What changed this quarter

Revenue was $658.7M in Q3 2026, up 10% year over year and up 5% from the previous quarter. Net product revenues was the largest line at 92% of revenue. Net product revenues added $62.0M year over year (up 11%), 102% of the total change. COMETRIQ declined 42%.

Operating profit was $268.4M, a 40.8% margin (up 1.2 points year over year). Of the extra revenue versus Q3 2025, 52% reached operating profit, above the 40% margin then. Total costs grew 8% against revenue growth of 10%. The fastest-growing cost line was Cost of revenue (+41%). Net earnings were $218.1M, up 13% year over year. The effective tax rate was 22.9%.

Operating cash flow was $280.0M (down 4% year over year), 128% of net earnings. Non-cash charges added back $6.9M of depreciation and amortization and $28.7M of share-based compensation. Working capital and other items added $26.2M. Capital expenditures of $2.5M left free cash flow of $277.5M.

Quarterly history

Exelixis revenue by quarterExelixis revenue by quarter$555MQ1 2025$568MQ2 2025$598MQ3 2025$599MQ4 2025$611MQ1 2026$629MQ2 2026$659MQ3 2026
Exelixis net earnings by quarterExelixis net earnings by quarter$160MQ1 2025$185MQ2 2025$194MQ3 2025$245MQ4 2025$210MQ1 2026$212MQ2 2026$218MQ3 2026
QuarterFormFiledRevenueY/YOp. marginNet earningsOp. cash flow
Q3 202610-QOct 29, 2026$659M+10%40.8%$218M$280M
Q2 202610-QAug 5, 2026$629M+11%39.5%$212M$308M
Q1 202610-QMay 5, 2026$611M+10%41.1%$210M$252M
Q4 202510-KFeb 10, 2026$599M+6%39.3%$245M$334M
Q3 202510-QNov 4, 2025$598M+11%39.6%$194M$290M
Q2 202510-QJul 28, 2025$568M-11%37.6%$185M$49.0M
Q1 202510-QMay 13, 2025$555M+31%33.6%$160M$211M

Charts

Exelixis: revenue growth, year over year and quarter over quarterExelixis: revenue growth, year over year and quarter over quarterY/YQ/Q+31%Q1 2025-11%+2%Q2 2025+11%+5%Q3 2025+6%+0%Q4 2025+10%+2%Q1 2026+11%+3%Q2 2026+10%+5%Q3 2026
Latest (Q3 2026): Y/Y +10%, Q/Q +5%.
Exelixis: where the cash came from (+) and went (−), TTM to Q3 2026Exelixis: where the cash came from (+) and went (−), TTM to Q3 2026Buybacks−$1.3BOperating cash flow$1.2BTaxes on employees’ shares−$78.8MOther investing$72.9MCash drawn (+) / kept (−)$71.5MShares issued$34.2MCapital spending−$12.0M
From the cash-flow statement as filed (SEC XBRL). Cash is fungible: the bars do not say which dollar paid for what.
Exelixis: profit against cash, quarter by quarterExelixis: profit against cash, quarter by quarterNet incomeOperating cash flow$140M$240MQ4 2024$160M$211MQ1 2025$185M$49.0MQ2 2025$194M$290MQ3 2025$245M$334MQ4 2025$210M$252MQ1 2026$212M$308MQ2 2026$218M$280MQ3 2026
Latest (Q3 2026): Net income $218M, Operating cash flow $280M.
Exelixis: diluted shares by fiscal yearExelixis: diluted shares by fiscal year318MFY2020322MFY2021325MFY2022321MFY2023296MFY2024282MFY2025
-11.4% since FY2020: buybacks shrank the count.
Exelixis in its industry: growth against margin (76 companies, SIC 2836)Exelixis in its industry: growth against margin (76 companies, SIC 2836)revenue growth, year over year →↑ operating marginmedian +9%median -100%AMGNGILDBIIBMRNANBIXHALOMGTXTECHVIRRGENTARSBCRXALECADMAKRYSIOVATWSTIPSCIMCRVISKVCELADPTNVAXKYMRGLUEIBRXAUTLAGENDNAPLXRXRXFENCCSBRCHRSIVVDCRSPEDITDTILVXRTSTRORGNXCCCCBSEMSCLXACOGTSHASRZNVYGRFDMTLENZALGSXFORELUTFATEOCGNSCTXCRBUCGONDBVTINBXMGXLCTXTCRXDYAIPRMEATRAVitro Biopharma, Inc.HUMARLAYPLURBEAMPROKCRDFAIMVIVSEXEL (+10%, 41%)
Biological Products, (No Diagnostic Substances); dot size is quarterly revenue; dashed lines are the industry's medians.

Interactive views

The same charts as the app — open one to draw it.

💵Where each $1 goesinteractive

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🌏Named in Asian annual reportsinteractive

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🔄Rotation against the market and its industry (RRG)interactive

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🔍Earnings qualityinteractive

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⚖️Fair value by methodinteractive

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🔭Outlook & guidanceinteractive

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📈Investments: gains and what it boughtinteractive

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🏭Its industry’s money flow (input-output)interactive

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Customers and suppliers named in filings

Sells to

About Exelixis

Exelixis, Inc. (Exelixis, we, our or us) is an oncology company innovating next-generation medicines and regimens at the forefront of cancer care. We have produced four marketed pharmaceutical products, two of which are formulations of our flagship molecule, cabozantinib, and we are steadily advancing and evolving our product pipeline portfolio, including our lead clinical asset, zanzalintinib, currently under review by the U.S. Food and Drug Administration (FDA) for the treatment of certain forms of colorectal cancer (CRC), as well as the focus of an extensive late-stage clinical development program in other indications.

In its own words, from its 10-K, filed Feb 10, 2026.

Exelixis against its Biological Products, (No Diagnostic Substances) peers

The largest companies of the same SEC industry, each at its latest quarter. Revenue growth: +10% against the peers' median +11%. Operating margin: 40.8% against the peers' median 35.8%.

CompanyQuarterRevenueY/YOp. margin
EXEL ExelixisQ3 2026$659M+10%40.8%
AMGN AmgenQ3 2026$10.4B+8%35.8%
GILD Gilead SciencesQ3 2026$8.3B+7%41.7%
BIIB BiogenQ3 2026$2.8B+11%-0.3%
MRNA ModernaQ3 2026$1.3B+29%9.9%
NBIX Neurocrine BiosciencesQ3 2026$1.1B+41%29.5%
HALO Halozyme TherapeuticsQ3 2026$493M+39%59.8%
MGTX MeiraGTx HoldingsQ2 2026$321M87×76.0%
TECH Bio-TechneQ1 FY27$300M+5%12.2%

Source: Exelixis 10-Q on SEC EDGAR · CIK 939767 · Biological Products, (No Diagnostic Substances)

Guidance and outlook

Exelixis Revenue: guidance against what was reportedExelixis Revenue: guidance against what was reportedguided rangereported (above / within / below)FY2024$2.2BFY2025$2.3BFY2026
Met or beat 2 of 2 guided periods. Grey: the last range guided before the figures came out; dot: the reported figure.
Exelixis Tax rate: guidance against what was reportedExelixis Tax rate: guidance against what was reportedguided rangereported (above / within / below)FY202423.5%FY202516.9%FY2026
Met or beat 1 of 2 guided periods. Grey: the last range guided before the figures came out; dot: the reported figure.

13F: who owns EXEL and who is buying

Largest holders of EXEL (13F)Largest holders of EXEL (13F)BlackRock$1.6BVanguard Group$1.1BRenaissance Technologies LLC$731MVanguard Portfolio Management LLC$655MAQR Capital Management LLC$599MVanguard Capital Management LLC$596MState Street$542MFuller & Thaler Asset Management$486MGeode Capital Management, LLC$416MD. E. Shaw$302M
Funds' net buying of EXEL by quarter (13F)Funds' net buying of EXEL by quarter (13F)−$38.1M2024-09−$91.3M2024-12$298M2025-03$401M2025-06−$292M2025-09$815M2025-12−$292M2026-03−$98.5M2026-06
Value of shares 13F filers added minus the value they sold, each quarter (quarters with most filings in).

More on EXEL

History

Every quarter: Q3 2026 results · Q2 2026 results · Q1 2026 results · Q4 2025 results · Q3 2025 results · Q2 2025 results · Q1 2025 results

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