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Exelixis vs Halozyme Therapeutics: EXEL and HALO compared

Exelixis is the larger company: $659M of revenue in its latest quarter (Q3 2026) against $493M for Halozyme Therapeutics (Q3 2026). Halozyme Therapeutics is growing faster (+39% against +10% a year earlier). Halozyme Therapeutics is more profitable, with an operating margin of 59.8% against 40.8%.

Exelixis vs Halozyme Therapeutics, latest quarterExelixis vs Halozyme Therapeutics, latest quarterExelixis (EXEL)Halozyme Therapeutics (HALO)Revenue$659M$493MRevenue growth, Y/Y+10%+39%Operating margin40.8%59.8%Net margin33.1%50.1%Free cash flow$277M$255M

Where the money goes: EXEL and HALO

Exelixis (EXEL) · Q3 2026

Exelixis, Q3 2026: revenue $659M (+10% year over year), operating margin 40.8%, net earnings $218M, operating cash flow $280M. The chart follows the revenue to costs, profit and cash.

Halozyme Therapeutics (HALO) · Q3 2026

Halozyme Therapeutics, Q3 2026: revenue $493M (+39% year over year), operating margin 59.8%, net earnings $247M, operating cash flow $258M. The chart follows the revenue to costs, profit and cash.

Exelixis revenue by segment, Q3 2026Exelixis revenue by segment, Q3 2026Net product revenues$605MCollaboration$53.8MCOMETRIQ$1.8M
Halozyme Therapeutics revenue by segment, Q3 2026Halozyme Therapeutics revenue by segment, Q3 2026Royalties$341MProduct sales, net$137MRevenues under collaborative agre…$14.6M
Exelixis (EXEL)Halozyme Therapeutics (HALO)
Latest quarterQ3 2026Q3 2026
Revenue$659M$493M
Revenue growth, Y/Y+10%+39%
Operating margin40.8%59.8%
Net earnings$218M$247M
Net margin33.1%50.1%
Operating cash flow$280M$258M
Free cash flow$277M$255M
Market value$17.8B$12.7B
P/E20.8×26.2×
Analysts’ mean target$61.57$109.67

Where the revenue comes from

Exelixis

Halozyme Therapeutics

Questions

Which is bigger, Exelixis or Halozyme Therapeutics?

Exelixis is the larger company: $659M of revenue in its latest quarter (Q3 2026) against $493M for Halozyme Therapeutics (Q3 2026).

Is Exelixis or Halozyme Therapeutics growing faster?

Halozyme Therapeutics is growing faster (+39% against +10% a year earlier).

Which is more profitable, Exelixis or Halozyme Therapeutics?

Halozyme Therapeutics is more profitable, with an operating margin of 59.8% against 40.8%.

More: Exelixis earnings · how Exelixis makes money · Halozyme Therapeutics earnings · how Halozyme Therapeutics makes money

From the companies' latest 10-Q, 10-K or earnings release (10-Q filed Oct 29, 2026; 10-Q filed Nov 5, 2026). Fiscal quarters can end on different dates. Not investment advice.