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Lantheus Holdings (LNTH) Q4 2025 earnings results (fourth quarter 2025)

10-K filed Feb 26, 2026

Lantheus Holdings (LNTH) reported revenue of $407M for the fourth quarter 2025 (Q4 2025), +4% from a year earlier and +6% from the quarter before. Operating margin was 19.0%, net earnings $54.1M (13.3% of revenue).

Revenue$407M
Year over year+4%
Quarter over quarter+6%
Operating margin19.0%
Net earnings$54.1M

Lantheus Holdings, Q4 2025: revenue $407M (+4% year over year), operating margin 19.0%, net earnings $54.1M, operating cash flow $90.2M. The chart follows the revenue to costs, profit and cash.

Q4 2025AmountQ/QY/Y
Revenue$407M+6%+4%
Gross profit$241M+8%-3%
Operating profit$77.2M+77%-32%
Net earnings$54.1M+95%—
Operating cash flow$90.2M-14%-43%
Free cash flow$81.4M—-42%

What changed

Revenue was $406.8M in Q4 2025, up 4% year over year and up 6% from the previous quarter. PYLARIFY was the largest line at 59% of revenue.

Gross margin was 59.2%, down 4.3 points from a year earlier. Operating profit was $77.2M, a 19.0% margin (down 10.1 points year over year). Operating profit fell $36.7M even though revenue rose $15.7M versus a year earlier, so costs grew faster than sales. Operating expenses grew 22% against revenue growth of 4%. Net earnings were $54.1M. The effective tax rate was 23.1%.

Operating cash flow was $90.2M (down 43% year over year), 167% of net earnings. Non-cash charges added back $22.8M of depreciation and amortization and $17.5M of share-based compensation. After capital expenditures ($8.8M), free cash flow as the company reports it was $81.4M.

Questions

What was Lantheus Holdings' revenue in the fourth quarter 2025?

Lantheus Holdings (LNTH) reported revenue of $407M for the fourth quarter 2025 (Q4 2025), +4% from a year earlier and +6% from the quarter before.

Was Lantheus Holdings profitable in the fourth quarter 2025?

Operating profit was $77.2M (19.0% of revenue) and net earnings $54.1M.

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Source: Lantheus Holdings 10-K on SEC EDGAR.