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Lyell Immunopharma (LYEL) Q3 2025 earnings results (third quarter 2025)

10-Q filed Nov 12, 2025

Lyell Immunopharma (LYEL) reported revenue of $15K for the third quarter 2025 (Q3 2025), -56% from a year earlier and +88% from the quarter before.

Revenue$15K
Year over year-56%
Quarter over quarter+88%
Operating margin—
Net earnings−$38.8M

Lyell Immunopharma, Q3 2025: revenue $15K (-56% year over year), net loss $38.8M, operating cash flow −$28.6M. The chart follows the revenue to costs, profit and cash.

Q3 2025AmountQ/QY/Y
Revenue$15K+88%-56%
Operating profit−$37.3M——
Net earnings−$38.8M——
Operating cash flow−$28.6M——

What changed

Revenue was $15K in Q3 2025, down 56% year over year and up 88% from the previous quarter.

Operating costs exceeded revenue by $37.3M, an operating margin of -248353.3%. Total costs fell 26% while revenue fell 56%. The quarter ended with a net loss of $38.8M, narrower than the previous quarter's $42.7M loss.

Operating cash flow was −$28.6M. Non-cash charges added back $2.6M of depreciation and amortization and $5.2M of share-based compensation. Working capital and other items added $2.5M. Capital expenditures of $62K exceeded it, leaving free cash flow of −$28.6M.

Questions

What was Lyell Immunopharma's revenue in the third quarter 2025?

Lyell Immunopharma (LYEL) reported revenue of $15K for the third quarter 2025 (Q3 2025), -56% from a year earlier and +88% from the quarter before.

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Source: Lyell Immunopharma 10-Q on SEC EDGAR.