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Seres Therapeutics (MCRB) Q4 2025 earnings results (fourth quarter 2025)

10-K filed Mar 12, 2026

Seres Therapeutics (MCRB) reported revenue of $438K for the fourth quarter 2025 (Q4 2025) and +25% from the quarter before.

Revenue$438K
Year over year—
Quarter over quarter+25%
Operating margin—
Net earnings−$15.3M

Seres Therapeutics, Q4 2025: revenue $438K, net loss $15.3M, operating cash flow −$14.7M. The chart follows the revenue to costs, profit and cash.

Q4 2025AmountQ/QY/Y
Revenue$438K+25%—
Operating profit−$19.4M——
Net earnings−$15.3M-287%—
Operating cash flow−$14.7M-767%—

What changed

Revenue was $438K in Q4 2025, up 25% from the previous quarter.

Operating costs exceeded revenue by $19.4M, an operating margin of -4424.0%. The quarter ended with a net loss of $15.3M, after a profit of $8.2M the previous quarter. Non-operating items added $4.0M, -26% of pre-tax earnings, so the bottom line overstates operating performance.

Operating cash flow was −$14.7M. Non-cash charges added back $1.0M of depreciation and amortization and $3.2M of share-based compensation. Working capital and other items used $3.5M. Capital expenditures of $29K exceeded it, leaving free cash flow of −$14.7M.

Questions

What was Seres Therapeutics' revenue in the fourth quarter 2025?

Seres Therapeutics (MCRB) reported revenue of $438K for the fourth quarter 2025 (Q4 2025) and +25% from the quarter before.

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Source: Seres Therapeutics 10-K on SEC EDGAR.