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Mirum Pharmaceuticals (MIRM) Q2 2025 earnings results (second quarter 2025)

10-Q filed Aug 6, 2025

Mirum Pharmaceuticals (MIRM) reported revenue of $128M for the second quarter 2025 (Q2 2025), +64% from a year earlier and +15% from the quarter before. Operating margin was -3.9%, net loss $5.9M (4.6% of revenue).

Revenue$128M
Year over year+64%
Quarter over quarter+15%
Operating margin-3.9%
Net earnings−$5.9M

Mirum Pharmaceuticals, Q2 2025: revenue $128M (+64% year over year), operating margin -3.9%, net loss $5.9M, operating cash flow $12.0M. The chart follows the revenue to costs, profit and cash.

Q2 2025AmountQ/QY/Y
Revenue$128M+15%+64%
Operating profit−$5.0M——
Net earnings−$5.9M——
Operating cash flow$12.0M——
Free cash flow$11.9M——

What changed

Revenue was $127.8M in Q2 2025, up 64% year over year and up 15% from the previous quarter. Livmarli was the largest line at 69% of revenue. Livmarli added $40.9M year over year (up 87%), 82% of the total change.

Operating costs exceeded revenue by $5.0M, an operating margin of -3.9%. Total costs grew 30% against revenue growth of 64%. The fastest-growing cost line was Research & development (+41%). The quarter ended with a net loss of $5.9M, narrower than the previous quarter's $14.7M loss.

Operating cash flow was $12.0M. Non-cash charges added back $6.1M of depreciation and amortization and $18.5M of share-based compensation. Working capital and other items used $6.6M. Capital expenditures of $126K left free cash flow of $11.9M.

Questions

What was Mirum Pharmaceuticals' revenue in the second quarter 2025?

Mirum Pharmaceuticals (MIRM) reported revenue of $128M for the second quarter 2025 (Q2 2025), +64% from a year earlier and +15% from the quarter before.

Was Mirum Pharmaceuticals profitable in the second quarter 2025?

Operating loss was $5.0M (-3.9% of revenue) and net loss $5.9M.

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Source: Mirum Pharmaceuticals 10-Q on SEC EDGAR.