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Mirum Pharmaceuticals (MIRM) Q3 2025 earnings results (third quarter 2025)

10-Q filed Nov 4, 2025

Mirum Pharmaceuticals (MIRM) reported revenue of $133M for the third quarter 2025 (Q3 2025), +47% from a year earlier and +4% from the quarter before. Operating margin was 2.0%, net earnings $2.9M (2.2% of revenue).

Revenue$133M
Year over year+47%
Quarter over quarter+4%
Operating margin2.0%
Net earnings$2.9M

Mirum Pharmaceuticals, Q3 2025: revenue $133M (+47% year over year), operating margin 2.0%, net earnings $2.9M, operating cash flow $39.7M. The chart follows the revenue to costs, profit and cash.

Q3 2025AmountQ/QY/Y
Revenue$133M+4%+47%
Operating profit$2.6M——
Net earnings$2.9M——
Operating cash flow$39.7M+230%+896%
Free cash flow$39.5M+231%+938%

What changed

Revenue was $133.0M in Q3 2025, up 47% year over year and up 4% from the previous quarter. Livmarli was the largest line at 69% of revenue. Livmarli added $33.1M year over year (up 56%), 78% of the total change.

Operating profit was $2.6M, a 2.0% margin (up 16.0 points year over year). Total costs grew 27% against revenue growth of 47%. The fastest-growing cost line was Research & development (+35%). Net earnings were $2.9M. The effective tax rate was -9.9%.

Operating cash flow was $39.7M (up 896% year over year), 1366% of net earnings. Non-cash charges added back $6.1M of depreciation and amortization and $18.1M of share-based compensation. Working capital and other items added $12.6M. Capital expenditures of $187K left free cash flow of $39.5M.

Questions

What was Mirum Pharmaceuticals' revenue in the third quarter 2025?

Mirum Pharmaceuticals (MIRM) reported revenue of $133M for the third quarter 2025 (Q3 2025), +47% from a year earlier and +4% from the quarter before.

Was Mirum Pharmaceuticals profitable in the third quarter 2025?

Operating profit was $2.6M (2.0% of revenue) and net earnings $2.9M.

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Source: Mirum Pharmaceuticals 10-Q on SEC EDGAR.