Filing Flows › Orasure Technologies (OSUR) › Q4 2025
Orasure Technologies (OSUR) Q4 2025 earnings results (fourth quarter 2025)
10-K filed Mar 9, 2026
Orasure Technologies (OSUR) reported revenue of $26.8M for the fourth quarter 2025 (Q4 2025), -29% from a year earlier and -1% from the quarter before. Operating margin was -75.1%, net loss $19.3M (72.1% of revenue).
Orasure Technologies, Q4 2025: revenue $26.8M (-28% year over year), operating margin -75.1%, net loss $19.3M, operating cash flow −$9.0M. The chart follows the revenue to costs, profit and cash.
| Q4 2025 | Amount | Q/Q | Y/Y |
|---|---|---|---|
| Revenue | $26.8M | -1% | -29% |
| Operating profit | −$20.1M | — | — |
| Net earnings | −$19.3M | — | — |
| Operating cash flow | −$9.0M | — | -8353% |
What changed
Revenue was $26.8M in Q4 2025, down 29% year over year and down 1% from the previous quarter. Products and services was the largest line at 93% of revenue.
Gross margin was 41.0%, up 4.8 points from Q4 2024. Operating costs exceeded revenue by $20.1M, an operating margin of -75.1%. Operating expenses grew 20% against a revenue fall of 29%. The fastest-growing cost line was Research & development (+88%). The quarter ended with a net loss of $19.3M, wider than the previous quarter's $13.7M loss.
Operating cash flow was −$9.0M. Non-cash charges added back $2.4M of depreciation and amortization and $1.5M of share-based compensation. Working capital and other items added $6.4M. Capital expenditures of $922K exceeded it, leaving free cash flow of −$9.9M.
Questions
What was Orasure Technologies' revenue in the fourth quarter 2025?
Orasure Technologies (OSUR) reported revenue of $26.8M for the fourth quarter 2025 (Q4 2025), -29% from a year earlier and -1% from the quarter before.
Was Orasure Technologies profitable in the fourth quarter 2025?
Operating loss was $20.1M (-75.1% of revenue) and net loss $19.3M.