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Prelude Therapeutics (PRLD) Q4 2024 earnings results (fourth quarter 2024)

10-K filed Mar 10, 2025

Prelude Therapeutics (PRLD) reported revenue of $4.0M for the fourth quarter 2024 (Q4 2024) and +33% from the quarter before. Operating margin was -845.8%, net loss $28.7M (718.3% of revenue).

Revenue$4.0M
Year over year—
Quarter over quarter+33%
Operating margin-845.8%
Net earnings−$28.7M

Prelude Therapeutics, Q4 2024: revenue $4.0M, operating margin -845.8%, net loss $28.7M, operating cash flow −$20.7M. The chart follows the revenue to costs, profit and cash.

Q4 2024AmountQ/QY/Y
Revenue$4.0M+33%—
Operating profit−$33.8M——
Net earnings−$28.7M——
Operating cash flow−$20.7M——

What changed

Revenue was $4.0M in Q4 2024, up 33% from the previous quarter.

Operating costs exceeded revenue by $33.8M, an operating margin of -845.8%. The quarter ended with a net loss of $28.7M, narrower than the previous quarter's $32.3M loss.

Operating cash flow was −$20.7M. Non-cash charges added back $489K of depreciation and amortization and $3.8M of share-based compensation. Working capital and other items added $3.7M. Capital expenditures of $53K exceeded it, leaving free cash flow of −$20.8M.

Questions

What was Prelude Therapeutics' revenue in the fourth quarter 2024?

Prelude Therapeutics (PRLD) reported revenue of $4.0M for the fourth quarter 2024 (Q4 2024) and +33% from the quarter before.

Was Prelude Therapeutics profitable in the fourth quarter 2024?

Operating loss was $33.8M (-845.8% of revenue) and net loss $28.7M.

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Source: Prelude Therapeutics 10-K on SEC EDGAR.