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Prime Medicine (PRME) Q1 2025 earnings results (first quarter 2025)

10-Q filed May 8, 2025

Prime Medicine (PRME) reported revenue of $1.5M for the first quarter 2025 (Q1 2025), +146% from a year earlier and -33% from the quarter before.

Revenue$1.5M
Year over year+146%
Quarter over quarter-33%
Operating margin—
Net earnings−$51.9M

Prime Medicine, Q1 2025: revenue $1.5M (+146% year over year), net loss $51.9M, operating cash flow −$48.9M. The chart follows the revenue to costs, profit and cash.

Q1 2025AmountQ/QY/Y
Revenue$1.5M-33%+146%
Operating profit−$52.4M——
Net earnings−$51.9M——
Operating cash flow−$48.9M-401%—

What changed

Revenue was $1.5M in Q1 2025, up 146% year over year and down 33% from the previous quarter.

Operating costs exceeded revenue by $52.4M, an operating margin of -3603.3%. Total costs grew 10% against revenue growth of 146%. The fastest-growing cost line was General & admin (+19%). The quarter ended with a net loss of $51.9M, wider than the previous quarter's $42.3M loss.

Operating cash flow was −$48.9M. Non-cash charges added back $1.7M of depreciation and amortization and $5.7M of share-based compensation. Working capital and other items used $4.3M. Capital expenditures of $2.4M exceeded it, leaving free cash flow of −$51.3M.

Questions

What was Prime Medicine's revenue in the first quarter 2025?

Prime Medicine (PRME) reported revenue of $1.5M for the first quarter 2025 (Q1 2025), +146% from a year earlier and -33% from the quarter before.

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Source: Prime Medicine 10-Q on SEC EDGAR.