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Prime Medicine (PRME) Q2 2025 earnings results (second quarter 2025)

10-Q filed Aug 7, 2025

Prime Medicine (PRME) reported revenue of $1.1M for the second quarter 2025 (Q2 2025) and -23% from the quarter before.

Revenue$1.1M
Year over year—
Quarter over quarter-23%
Operating margin—
Net earnings−$52.6M

Prime Medicine, Q2 2025: revenue $1.1M, net loss $52.6M, operating cash flow −$41.4M. The chart follows the revenue to costs, profit and cash.

Q2 2025AmountQ/QY/Y
Revenue$1.1M-23%—
Operating profit−$53.4M——
Net earnings−$52.6M——
Operating cash flow−$41.4M——

What changed

Revenue was $1.1M in Q2 2025, down 23% from the previous quarter.

Operating costs exceeded revenue by $53.4M, an operating margin of -4787.2%. The quarter ended with a net loss of $52.6M, wider than the previous quarter's $51.9M loss.

Operating cash flow was −$41.4M. Non-cash charges added back $1.9M of depreciation and amortization and $6.3M of share-based compensation. Working capital and other items added $3.0M. Capital expenditures of $1.6M exceeded it, leaving free cash flow of −$43.0M.

Questions

What was Prime Medicine's revenue in the second quarter 2025?

Prime Medicine (PRME) reported revenue of $1.1M for the second quarter 2025 (Q2 2025) and -23% from the quarter before.

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Source: Prime Medicine 10-Q on SEC EDGAR.