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Prime Medicine (PRME) Q3 2025 earnings results (third quarter 2025)

10-Q filed Nov 7, 2025

Prime Medicine (PRME) reported revenue of $1.2M for the third quarter 2025 (Q3 2025), +486% from a year earlier and +10% from the quarter before.

Revenue$1.2M
Year over year+486%
Quarter over quarter+10%
Operating margin—
Net earnings−$50.6M

Prime Medicine, Q3 2025: revenue $1.2M (+486% year over year), net loss $50.6M, operating cash flow −$35.0M. The chart follows the revenue to costs, profit and cash.

Q3 2025AmountQ/QY/Y
Revenue$1.2M+10%+486%
Operating profit−$54.0M——
Net earnings−$50.6M——
Operating cash flow−$35.0M——

What changed

Revenue was $1.2M in Q3 2025, up 486% year over year and up 10% from the previous quarter.

Operating costs exceeded revenue by $54.0M, an operating margin of -4406.0%. Total costs grew 1% against revenue growth of 486%. The quarter ended with a net loss of $50.6M, narrower than the previous quarter's $52.6M loss.

Operating cash flow was −$35.0M. Non-cash charges added back $1.9M of depreciation and amortization and $12.7M of share-based compensation. Capital expenditures of $247K exceeded it, leaving free cash flow of −$35.3M.

Questions

What was Prime Medicine's revenue in the third quarter 2025?

Prime Medicine (PRME) reported revenue of $1.2M for the third quarter 2025 (Q3 2025), +486% from a year earlier and +10% from the quarter before.

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Source: Prime Medicine 10-Q on SEC EDGAR.