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Pyxis Oncology (PYXS) Q2 2025 earnings results (second quarter 2025)

10-Q filed Aug 14, 2025

Pyxis Oncology (PYXS) reported revenue of $2.8M for the second quarter 2025 (Q2 2025). Operating margin was -700.4%, net loss $18.4M (650.9% of revenue).

Revenue$2.8M
Year over year—
Quarter over quarter—
Operating margin-700.4%
Net earnings−$18.4M

Pyxis Oncology, Q2 2025: revenue $2.8M, operating margin -700.4%, net loss $18.4M, operating cash flow −$17.3M. The chart follows the revenue to costs, profit and cash.

Q2 2025AmountQ/QY/Y
Revenue$2.8M——
Operating profit−$19.8M——
Net earnings−$18.4M——
Operating cash flow−$17.3M——

What changed

Revenue was $2.8M in Q2 2025.

Operating costs exceeded revenue by $19.8M, an operating margin of -700.4%. The quarter ended with a net loss of $18.4M.

Operating cash flow was −$17.3M. Non-cash charges added back $535K of depreciation and amortization and $3.0M of share-based compensation. Working capital and other items used $2.5M.

Questions

What was Pyxis Oncology's revenue in the second quarter 2025?

Pyxis Oncology (PYXS) reported revenue of $2.8M for the second quarter 2025 (Q2 2025).

Was Pyxis Oncology profitable in the second quarter 2025?

Operating loss was $19.8M (-700.4% of revenue) and net loss $18.4M.

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Source: Pyxis Oncology 10-Q on SEC EDGAR.