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Who owns Pyxis Oncology (PYXS) stock

77 funds reported Pyxis Oncology (PYXS) shares in their latest 13F filings, worth $101M in all. The largest holder is GordonMD Global Investments LP ($30.2M). Last quarter 31 funds added to their stakes and 32 cut them.

Largest holders of PYXS (13F)Largest holders of PYXS (13F)GordonMD Global Investments LP$30.2MPfizer$19.5MLaurion Capital Management LP$11.6MVanguard Capital Management LLC$6.2MHealthInvest Partners AB$2.9MVanguard Group$2.7MBlackRock$2.6MPalo Alto Investors LP$2.6MMarshall Wace, LLP$2.5MRenaissance Technologies LLC$2.3M

Largest holders (13F)

FundSharesValueChangeQuarter
GordonMD Global Investments LP10,024,909$30.2Mincrease2026-06-30
Pfizer7,032,770$19.5Munchanged2026-06-30
Laurion Capital Management LP4,989,888$11.6Mincrease2026-09-30
Vanguard Capital Management LLC2,075,997$6.2Mincrease2026-06-30
HealthInvest Partners AB966,459$2.9Mincrease2026-06-30
Vanguard Group2,335,768$2.7Mincrease2025-12-31
BlackRock867,934$2.6Mincrease2026-06-30
Palo Alto Investors LP864,277$2.6Mdecrease2026-06-30
Marshall Wace, LLP830,544$2.5Mincrease2026-06-30
Renaissance Technologies LLC772,232$2.3Mdecrease2026-06-30
Geode Capital Management, LLC591,849$1.8Mdecrease2026-06-30
Woodline Partners LP523,999$1.6Mnew2026-06-30
683 Capital Management, LLC459,367$1.4Mdecrease2026-06-30
Jacobs Levy Equity Management428,606$1.3Mdecrease2026-06-30
Longaeva Partners L.P.353,582$1.1Mdecrease2026-06-30

Pyxis Oncology's latest quarter

Pyxis Oncology, Q4 2025: revenue $11.0M, operating margin -165.7%, net loss $18.1M, operating cash flow −$10.4M. The chart follows the revenue to costs, profit and cash.

Questions

Who owns the most PYXS stock?

By the latest 13F filings: GordonMD Global Investments LP ($30.2M); Pfizer ($19.5M); Laurion Capital Management LP ($11.6M); Vanguard Capital Management LLC ($6.2M); HealthInvest Partners AB ($2.9M).

What is the short interest in PYXS?

4,345,953 shares were sold short at the 2026-10-15 settlement, -11.06% of the float.

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Updated Nov 8, 2026. Read automatically from SEC filings and public data; errors are possible. Not investment advice.