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Schrodinger (SDGR) Q1 2026 earnings results (first quarter 2026)

10-Q filed May 5, 2026

Schrodinger (SDGR) reported revenue of $58.6M for the first quarter 2026 (Q1 2026), -2% from a year earlier and -33% from the quarter before. Operating margin was -83.3%, net loss $60.0M (102.5% of revenue).

Revenue$58.6M
Year over year-2%
Quarter over quarter-33%
Operating margin-83.3%
Net earnings−$60.0M

Schrodinger, Q1 2026: revenue $58.6M (-2% year over year), operating margin -83.3%, net loss $60.0M, operating cash flow −$14.8M. The chart follows the revenue to costs, profit and cash.

Q1 2026AmountQ/QY/Y
Revenue$58.6M-33%-2%
Operating profit−$48.8M——
Net earnings−$60.0M-285%—
Operating cash flow−$14.8M—-110%

What changed

Revenue was $58.6M in Q1 2026, down 2% year over year and down 33% from the previous quarter. Drug discovery was the largest line at 39% of revenue. On-premise software lost $11.2M year over year (down 44%), 1166% of the total change.

Gross margin was 50.4%, down 1.8 points from Q1 2025. Operating costs exceeded revenue by $48.8M, an operating margin of -83.3%. Operating expenses fell 4% while revenue fell 2%. The fastest-growing cost line was Sales & marketing (+12%). The quarter ended with a net loss of $60.0M, after a profit of $32.5M the previous quarter.

Operating cash flow was −$14.8M. Non-cash charges added back $1.5M of depreciation and amortization and $9.1M of share-based compensation. Working capital and other items added $34.6M. Capital expenditures of $2.5M exceeded it, leaving free cash flow of −$17.3M.

Questions

What was Schrodinger's revenue in the first quarter 2026?

Schrodinger (SDGR) reported revenue of $58.6M for the first quarter 2026 (Q1 2026), -2% from a year earlier and -33% from the quarter before.

Was Schrodinger profitable in the first quarter 2026?

Operating loss was $48.8M (-83.3% of revenue) and net loss $60.0M.

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Source: Schrodinger 10-Q on SEC EDGAR.