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Septerna (SEPN) earnings on Nov 9, 2026: what to expect

Septerna (SEPN) is expected to report earnings on Nov 9, 2026 (estimated), tomorrow, for the quarter ending Sep 30, 2026. Analysts expect EPS of −$0.40 (−$0.69 to −$0.24, 4 estimates) on revenue of $20.8M, against −$0.10 and $21.5M a year ago. It beat the EPS estimate in 50% of the quarters on record; Filing Flows' model gives it a 66% chance of beating next time.

Report dateNov 9, 2026 (estimated)
Days to go1
EPS estimate−$0.40
Revenue estimate$20.8M
Beat rate50%

What to watch

Last quarter (Q2 2026) the lines that make up revenue grew like this; the report shows whether the trend holds:

Septerna: revenue lines, growth year over year, Q2 2026Septerna: revenue lines, growth year over year, Q2 2026Revenue225×

Filing Flows' own estimate from the SEC figures — the same quarter last year times recent growth — is EPS −$0.10 on revenue of $55.1M, against the analysts' −$0.40.

The last report

Septerna reported revenue of $26.7M for the second quarter 2026 (225× Y/Y), net loss $13.0M. How it makes money → · Every quarter →

Septerna: EPS against the estimate, last 4 reportsSepterna: EPS against the estimate, last 4 reportsEstimateReported$0.79−$0.10Nov 25−$0.22−$0.24Mar 26−$0.27−$0.19May 26−$0.49−$0.29Aug 26
Latest (Aug 26): Estimate −$0.49, Reported −$0.29.

Septerna's latest quarter

Septerna, Q2 2026: revenue $26.7M (225× year over year), operating margin -62.9%, net loss $13.0M, operating cash flow −$22.2M. The chart follows the revenue to costs, profit and cash.

Questions

When does SEPN report earnings?

Septerna is expected to report on Nov 9, 2026 (estimated).

What are analysts expecting from Septerna?

EPS of −$0.40 and revenue of $20.8M for the quarter.

Does Septerna usually beat earnings?

It beat the consensus EPS estimate in 50% of the quarters on record.

Open the interactive view →

Updated Nov 8, 2026. Read automatically from SEC filings and public data; errors are possible. Not investment advice.