Filing Flows › Septerna (SEPN) › Q1 2025
Septerna (SEPN) Q1 2025 earnings results (first quarter 2025)
10-Q filed May 15, 2025
Septerna (SEPN) reported revenue of $219K for the first quarter 2025 (Q1 2025), -31% from a year earlier and +3% from the quarter before.
Septerna, Q1 2025: revenue $219K (-31% year over year), net loss $21.5M, operating cash flow −$23.3M. The chart follows the revenue to costs, profit and cash.
| Q1 2025 | Amount | Q/Q | Y/Y |
|---|---|---|---|
| Revenue | $219K | +3% | -31% |
| Operating profit | −$25.9M | — | — |
| Net earnings | −$21.5M | — | — |
| Operating cash flow | −$23.3M | — | — |
What changed
Revenue was $219K in Q1 2025, down 31% year over year and up 3% from the previous quarter.
Operating costs exceeded revenue by $25.9M, an operating margin of -11831.1%. Total costs grew 65% against a revenue fall of 31%. The fastest-growing cost line was General & admin (+158%). The quarter ended with a net loss of $21.5M, wider than the previous quarter's $20.7M loss. Non-operating items added $4.4M, -21% of pre-tax earnings, so the bottom line overstates operating performance.
Operating cash flow was −$23.3M. Non-cash charges added back $397K of depreciation and amortization and $1.5M of share-based compensation. Working capital and other items used $3.7M. Capital expenditures of $382K exceeded it, leaving free cash flow of −$23.7M.
Questions
What was Septerna's revenue in the first quarter 2025?
Septerna (SEPN) reported revenue of $219K for the first quarter 2025 (Q1 2025), -31% from a year earlier and +3% from the quarter before.
Source: Septerna 10-Q on SEC EDGAR.