Filing Flows › Septerna (SEPN) › Q3 2026 › vs Q3 2025
Septerna (SEPN) Q3 2026 vs Q3 2025 (year over year)
Septerna's revenue fell $2.6M (-12%) from $21.5M in Q3 2025 to $18.9M in Q3 2026.
Septerna, Q3 2026: revenue $18.9M (-12% year over year), operating margin -144.2%, net loss $26.6M, operating cash flow −$13.8M. The chart draws each line against Q3 2025, the increases inside each band.
Every line
| Line | Q3 2026 | Q3 2025 | Change | % |
|---|---|---|---|---|
| Revenue | $18.9M | $21.5M | −$2.6M | -12% |
| Other income, net | $5.3M | $5.6M | −$299K | -5% |
| Net loss | $26.6M | −$8.2M | $34.8M | — |
| Costs & expenses | $50.7M | $27.1M | $23.7M | +88% |
| Operating costs | $46.1M | $18.9M | $27.2M | +144% |
| Income tax | $4.6M | $0 | $4.6M | — |
| Operating cash sources | $26.6M | −$8.2M | $34.8M | — |
| Depreciation & amortization | $394K | $401K | −$7K | -2% |
| Share-based compensation | $5.9M | $2.5M | $3.4M | +134% |
| Working capital & other | $6.5M | $158M | −$151M | -96% |
| Cash used in operations | $13.8M | −$169M | $183M | — |
| Net loss absorbed | $26.6M | −$8.2M | $34.8M | — |
Questions
How much did Septerna's revenue grow year over year in Q3 2026?
Septerna's revenue fell $2.6M (-12%) from $21.5M in Q3 2025 to $18.9M in Q3 2026.