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Syndax Pharmaceuticals (SNDX) Q1 2025 earnings results (first quarter 2025)

10-Q filed May 5, 2025

Syndax Pharmaceuticals (SNDX) reported revenue of $20.0M for the first quarter 2025 (Q1 2025) and +161% from the quarter before. Operating margin was -417.9%, net loss $84.8M (423.3% of revenue).

Revenue$20.0M
Year over year—
Quarter over quarter+161%
Operating margin-417.9%
Net earnings−$84.8M

Syndax Pharmaceuticals, Q1 2025: revenue $20.0M, operating margin -417.9%, net loss $84.8M, operating cash flow −$95.2M. The chart follows the revenue to costs, profit and cash.

Q1 2025AmountQ/QY/Y
Revenue$20.0M+161%—
Operating profit−$83.8M——
Net earnings−$84.8M——
Operating cash flow−$95.2M——

What changed

Revenue was $20.0M in Q1 2025, up 161% from the previous quarter.

Operating costs exceeded revenue by $83.8M, an operating margin of -417.9%. The quarter ended with a net loss of $84.8M, narrower than the previous quarter's $94.2M loss.

Operating cash flow was −$95.2M. Non-cash charges added back $10.4M of share-based compensation. Working capital and other items used $20.7M.

Questions

What was Syndax Pharmaceuticals' revenue in the first quarter 2025?

Syndax Pharmaceuticals (SNDX) reported revenue of $20.0M for the first quarter 2025 (Q1 2025) and +161% from the quarter before.

Was Syndax Pharmaceuticals profitable in the first quarter 2025?

Operating loss was $83.8M (-417.9% of revenue) and net loss $84.8M.

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Source: Syndax Pharmaceuticals 10-Q on SEC EDGAR.