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Syndax Pharmaceuticals (SNDX) earnings and revenue breakdown

Latest: Q3 2026 · 10-Q filed Nov 2, 2026 · Syndax Pharmaceuticals (SNDX) Q3 2026 earnings results →

Q3 2026 Revenue up 82% year over year to $83.3M · 59¢ of every $1 of revenue lost · operating margin -50.3%

Syndax Pharmaceuticals made $83.3M in Q3 2026 (+82% Y/Y): Product $60.7M, Collaboration Revenue $22.6M. Operating margin -50.3%, net loss $49.4M. See where every dollar goes — costs, profit and cash — as a Sankey from the 10-Q filed Nov 2, 2026.

Revenue$83.3M
Year over year+82%
Operating margin-50.3%
Net earnings−$49.4M
Operating cash flow−$27.3M

Drawing the Sankey…

Open the interactive Sankey → click any line for what the company wrote about it, compare Y/Y and Q/Q, export as PNG or PDF

What changed this quarter

Revenue was $83.3M in Q3 2026, up 82% year over year and up 14% from the previous quarter. Product was the largest line at 73% of revenue. Product added $28.7M year over year (up 90%), 77% of the total change.

Operating costs exceeded revenue by $41.9M, an operating margin of -50.3%. Total costs grew 21% against revenue growth of 82%. The fastest-growing cost line was Other operating costs (+566%). The quarter ended with a net loss of $49.4M, wider than the previous quarter's $49.4M loss.

Operating cash flow was −$27.3M. Non-cash charges added back $6.0M of depreciation and $15.3M of share-based compensation.

Quarterly history

Syndax Pharmaceuticals revenue by quarterSyndax Pharmaceuticals revenue by quarter$20.0MQ1 2025$38.0MQ2 2025$45.9MQ3 2025$68.7MQ4 2025$64.9MQ1 2026$72.8MQ2 2026$83.3MQ3 2026
Syndax Pharmaceuticals net earnings by quarterSyndax Pharmaceuticals net earnings by quarter−$84.8MQ1 2025−$71.8MQ2 2025−$60.7MQ3 2025−$68.0MQ4 2025−$42.7MQ1 2026−$49.4MQ2 2026−$49.4MQ3 2026
QuarterFormFiledRevenueY/YOp. marginNet earningsOp. cash flow
Q3 202610-QNov 2, 2026$83.3M+82%-50.3%−$49.4M−$27.3M
Q2 202610-QAug 4, 2026$72.8M+92%-54.9%−$49.4M−$30.3M
Q1 202610-QApr 30, 2026$64.9M+224%-52.7%−$42.7M−$50.3M
Q4 202510-KFeb 26, 2026$68.7M+795%-91.0%−$68.0M−$69.5M
Q3 202510-QNov 3, 2025$45.9M+267%-125.2%−$60.7M−$70.5M
Q2 202510-QAug 4, 2025$38.0M+984%-182.7%−$71.8M−$87.8M
Q1 202510-QMay 5, 2025$20.0M—-417.9%−$84.8M−$95.2M

Charts

Syndax Pharmaceuticals: revenue growth, year over year and quarter over quarterSyndax Pharmaceuticals: revenue growth, year over year and quarter over quarterY/YQ/Q+400%+89%Q2 2025+267%+21%Q3 2025+400%+50%Q4 2025+224%-6%Q1 2026+92%+12%Q2 2026+82%+14%Q3 2026
Latest (Q3 2026): Y/Y +82%, Q/Q +14%.
Syndax Pharmaceuticals: where the cash came from (+) and went (−), TTM to Q3 2026Syndax Pharmaceuticals: where the cash came from (+) and went (−), TTM to Q3 2026Other financing$245MOperating cash flow−$177MOther investing−$73.4MShares issued$24.7MCash drawn (+) / kept (−)−$19.0M
From the cash-flow statement as filed (SEC XBRL). Cash is fungible: the bars do not say which dollar paid for what.
Syndax Pharmaceuticals: profit against cash, quarter by quarterSyndax Pharmaceuticals: profit against cash, quarter by quarterNet incomeOperating cash flow−$94.2M−$57.4MQ4 2024−$84.8M−$95.2MQ1 2025−$71.8M−$87.8MQ2 2025−$60.7M−$70.5MQ3 2025−$68.0M−$69.5MQ4 2025−$42.7M−$50.3MQ1 2026−$49.4M−$30.3MQ2 2026−$49.4M−$27.3MQ3 2026
Latest (Q3 2026): Net income −$49.4M, Operating cash flow −$27.3M.
Syndax Pharmaceuticals: diluted shares by fiscal yearSyndax Pharmaceuticals: diluted shares by fiscal year41MFY202054MFY202161MFY202270MFY202386MFY202487MFY2025
+109.7% since FY2020: more shares outstanding (issuance, stock pay).
Syndax Pharmaceuticals in its industry: growth against margin (225 companies, SIC 2834)Syndax Pharmaceuticals in its industry: growth against margin (225 companies, SIC 2834)revenue growth, year over year →↑ operating marginmedian +11%median -50%JNJLLYMRKABBVPFEBMYABTREGNTEVAVTRSVRTXBHCZTSONCOGNALNYELANJAZZBMRNPRGOAMRXUTHRRPRXNRIXINSMKeenova Therapeutics plcALKSMDGLPAHCSRPTPTCTINDVBBIOACADCORTPBHANIPKNSAPTGXHRMYIONSAXSMTGTXSUPNTVTXCOLLVREOFAMPHMIRMPCRXRARELQDAARQTIRWDARDXNATRXNCREBSZLABXERSINVACRMDMNKDRYTMURGNPHATAUPHRIGLLGNDEOLSARWRPGENHROWVNDAOPKSDGRGERNETONAGIOPBYITNGXCYRXCYTKMRVIORGONUVBLFVNSIGAKROSAMRNZVRASPRYHRTXAKBABCYCKPTIGYREMGNXELTPSEPNVRDNLFCRCrinetics Pharmaceuticals, Inc.VSTMKURATBPHLABADCTNAMSFBIOXLODERMARCTRMTIAYTUFHTXENTATNXPOCULASMBWVEAPMDBFRIABEOSTOKLXRXCAPRIDYANKTRZOMDFINBPJANXSBFMGOSSETSTRCUSCPIXLIFDCUEAQSTPRAXWHWKVERUEMMAGENBVRCACELUQUREZYMEEQABCLIMNMKYNBAKTSRNACVSICNTBTRAWISCOEVFMTVRDLPCNCAMPAtaiBeckley Inc.CTMXALMSPMHSACRSVTGNROIVKRROJAGXENSCKRSAABUSPRPHSTTKCPHITRDATXMDGOVXNWBOBIOEUPBIRDOVIDSPRBXBIOPRTAMCRBARVNMNOVSLNIGCBIOALGVNDNTHCPMDSPRORFLCOYASCYXBFRGSXTPBTAIQHCWBSERYARWRNACRGBPAVTXCLNNNTHIHINDAAGHALTONCOCRVOSKVIBOLTBDPTLYELIBOPULMSNDX (+82%, -50%)
Pharmaceutical Preparations; dot size is quarterly revenue; dashed lines are the industry's medians.

Interactive views

The same charts as the app — open one to draw it.

💵Where each $1 goesinteractive

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🌏Named in Asian annual reportsinteractive

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🔄Rotation against the market and its industry (RRG)interactive

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🔍Earnings qualityinteractive

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⚖️Fair value by methodinteractive

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🔭Outlook & guidanceinteractive

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📈Investments: gains and what it boughtinteractive

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🏭Its industry’s money flow (input-output)interactive

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About Syndax Pharmaceuticals

Syndax Pharmaceuticals is a commercial-stage biopharmaceutical company advancing innovative cancer therapies. Highlights of the Company's pipeline include Revuforj ® (revumenib), an FDA-approved menin inhibitor, and Niktimvo™ (axatilimab-csfr), an FDA-approved monoclonal antibody that blocks the colony stimulating factor 1 (CSF-1) receptor. Fueled by our commitment to reimagining cancer care, Syndax is working to unlock the full potential of its pipeline and is conducting several clinical trials across the continuum of treatment. For more information, please visit www.syndax.com/ or follow the Company on X and LinkedIn .

In its own words, from its 8-K, filed Aug 4, 2026.

Syndax Pharmaceuticals against its Pharmaceutical Preparations peers

The largest companies of the same SEC industry, each at its latest quarter. Revenue growth: +82% against the peers' median +10%. Operating margin: -50.3% against the peers' median 20.4%.

CompanyQuarterRevenueY/YOp. margin
SNDX Syndax PharmaceuticalsQ3 2026$83.3M+82%-50.3%
JNJ Johnson & JohnsonQ3 2026$25.4B+6%0.1%
LLY ELI LillyQ3 2026$24.4B+39%34.5%
MRK MerckQ3 2026$18.1B+5%30.7%
ABBV AbbVieQ3 2026$17.4B+10%36.0%
PFE PfizerQ3 2026$16.6B-0.4%20.4%
BMY Bristol Myers SquibbQ3 2026$13.1B+7%19.4%
ABT Abbott LaboratoriesQ3 2026$13.0B+14%10.4%
REGN Regeneron PharmaceuticalsQ3 2026$5.1B+36%40.0%

Source: Syndax Pharmaceuticals 10-Q on SEC EDGAR · CIK 1395937 · Pharmaceutical Preparations

Guidance and outlook

Syndax Pharmaceuticals: what its forward-looking statements are about (10-Q filed 2026-11-02)Syndax Pharmaceuticals: what its forward-looking statements are about (10-Q filed 2026-11-02)Other16Costs5Financing3Demand2Legal & regulation1Margins1
28 statements; tone -0.04 (−1 all cautious, +1 all confident); 4 hedged.
Syndax Pharmaceuticals: outlook statements against the filing beforeSyndax Pharmaceuticals: outlook statements against the filing beforeConfident2Cautious3

13F: who owns SNDX and who is buying

Largest holders of SNDX (13F)Largest holders of SNDX (13F)BlackRock$197MKynam Capital Management, LP$176MVanguard Group$131MGoldman Sachs Group$128MState Street$124MBank of America$88.4MVanguard Capital Management LLC$85.9MDeerfield Management Company, L.P…$82.6MEversept Partners, LP$61.2MGeode Capital Management, LLC$56.5M
Funds' net buying of SNDX by quarter (13F)Funds' net buying of SNDX by quarter (13F)$28.8M2024-09$54.2M2024-12$43.7M2025-03$18.4M2025-06−$14.9M2025-09−$68.1M2025-12$14.8M2026-03$160M2026-06
Value of shares 13F filers added minus the value they sold, each quarter (quarters with most filings in).

More on SNDX

History

Every quarter: Q3 2026 results · Q2 2026 results · Q1 2026 results · Q4 2025 results · Q3 2025 results · Q2 2025 results · Q1 2025 results

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