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Syndax Pharmaceuticals (SNDX) Q2 2026 earnings results (second quarter 2026)

10-Q filed Aug 4, 2026

Syndax Pharmaceuticals (SNDX) reported revenue of $72.8M for the second quarter 2026 (Q2 2026), +92% from a year earlier and +12% from the quarter before. Operating margin was -54.9%, net loss $49.4M (67.8% of revenue).

Revenue$72.8M
Year over year+92%
Quarter over quarter+12%
Operating margin-54.9%
Net earnings−$49.4M

Syndax Pharmaceuticals, Q2 2026: revenue $72.8M (+92% year over year), operating margin -54.9%, net loss $49.4M, operating cash flow −$30.3M. The chart follows the revenue to costs, profit and cash.

Q2 2026AmountQ/QY/Y
Revenue$72.8M+12%+92%
Operating profit−$40.0M——
Net earnings−$49.4M——
Operating cash flow−$30.3M——

What changed

Revenue was $72.8M in Q2 2026, up 92% year over year and up 12% from the previous quarter. Product was the largest line at 75% of revenue. Product added $26.1M year over year (up 91%), 75% of the total change.

Operating costs exceeded revenue by $40.0M, an operating margin of -54.9%. Total costs grew 5% against revenue growth of 92%. The fastest-growing cost line was Other operating costs (+151%). The quarter ended with a net loss of $49.4M, wider than the previous quarter's $42.7M loss.

Operating cash flow was −$30.3M. Non-cash charges added back $5.0M of depreciation and $14.0M of share-based compensation.

Questions

What was Syndax Pharmaceuticals' revenue in the second quarter 2026?

Syndax Pharmaceuticals (SNDX) reported revenue of $72.8M for the second quarter 2026 (Q2 2026), +92% from a year earlier and +12% from the quarter before.

Was Syndax Pharmaceuticals profitable in the second quarter 2026?

Operating loss was $40.0M (-54.9% of revenue) and net loss $49.4M.

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Source: Syndax Pharmaceuticals 10-Q on SEC EDGAR.