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Is Syndax Pharmaceuticals (SNDX) a takeover target?

A leveraged buyout does not work for Syndax Pharmaceuticals on its latest figures: it has no positive EBITDA to borrow against (−$164M over the last 12 months, on revenue of $289M). Historically 5.3% of companies with its figures were bought within a year (1.05× the average).

Share price$13.97
Market value$1.3B
Enterprise value$707M
Cash$548M
Debt$0
Revenue, 12 months$289M
Revenue growth+159%
EBITDA, 12 months−$164M

Why a leveraged buyout does not fit

A leveraged buyout is paid for mostly with debt that the company's own cash flow repays. Syndax Pharmaceuticals' EBITDA over the last 12 months was −$164M on revenue of $289M, so there is nothing to lend against and nothing to repay a loan with: a buyer would have to pay almost entirely with its own money. That is the kind of deal another company — a strategic buyer that wants the products, the pipeline or the technology — makes, not a private-equity fund. The model therefore gives no buyout price.

What a takeover could cost

Takeovers in its sector paid a median premium of 35% over the share price before the deal (the middle half 22% to 45%), according to the 15 merger proxies and tender-offer responses on EDGAR that state a premium. At the median, Syndax Pharmaceuticals would cost about $18.86 a share, $1.7B for all its shares.

Premium%Price a shareAll shares
Low end (a quarter of deals paid less)22%$17.04$1.5B
Median35%$18.86$1.7B
High end (a quarter paid more)45%$20.26$1.8B

The odds, from history

Historically 5.3% of companies with its figures were bought within a year (1.05× the average). Its figures put it in decile 6 of 10 (10 = the most likely to be bought). The odds come from a model of every merger proxy, tender-offer response and going-private statement filed on EDGAR since 2011, set against each company's size, margins, debt, cash flow and growth the year before.

Syndax Pharmaceuticals' latest quarter

Syndax Pharmaceuticals, Q3 2026: revenue $83.3M (+82% year over year), operating margin -50.3%, net loss $49.4M, operating cash flow −$27.3M. The chart follows the revenue to costs, profit and cash.

Questions

Is Syndax Pharmaceuticals being acquired?

No headline, 8-K or 13D about a sale is on file in the last year.

Could private equity buy Syndax Pharmaceuticals?

A leveraged buyout does not work for Syndax Pharmaceuticals on its latest figures: it has no positive EBITDA to borrow against (−$164M over the last 12 months, on revenue of $289M). With no cash flow to repay a loan, a buyer would pay almost entirely with its own money: a deal for another company (a strategic buyer), not for a private-equity fund.

What would a takeover of Syndax Pharmaceuticals cost?

Takeovers in its sector paid a median premium of 35% over the share price before the deal (the middle half 22% to 45%), according to the 15 merger proxies and tender-offer responses on EDGAR that state a premium. At the median, Syndax Pharmaceuticals would cost about $18.86 a share, $1.7B for all its shares.

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Updated Nov 8, 2026. Read automatically from SEC filings and public data; errors are possible. Not investment advice.