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Taysha Gene Therapies (TSHA) Q1 2025 earnings results (first quarter 2025)

10-Q filed May 15, 2025

Taysha Gene Therapies (TSHA) reported revenue of $2.3M for the first quarter 2025 (Q1 2025), -33% from a year earlier and +14% from the quarter before. Operating margin was -930.5%, net loss $21.5M (935.2% of revenue).

Revenue$2.3M
Year over year-33%
Quarter over quarter+14%
Operating margin-930.5%
Net earnings−$21.5M

Taysha Gene Therapies, Q1 2025: revenue $2.3M (-32% year over year), operating margin -930.5%, net loss $21.5M, operating cash flow −$22.0M. The chart follows the revenue to costs, profit and cash.

Q1 2025AmountQ/QY/Y
Revenue$2.3M+14%-33%
Operating profit−$21.4M——
Net earnings−$21.5M——
Operating cash flow−$22.0M——

What changed

Revenue was $2.3M in Q1 2025, down 33% year over year and up 14% from the previous quarter.

Operating costs exceeded revenue by $21.4M, an operating margin of -930.5%. Total costs fell 14% while revenue fell 33%. The fastest-growing cost line was General & admin (+15%). The quarter ended with a net loss of $21.5M, wider than the previous quarter's $18.8M loss.

Operating cash flow was −$22.0M. Non-cash charges added back $283K of depreciation and $3.3M of share-based compensation. Working capital and other items used $4.1M. Capital expenditures of $378K exceeded it, leaving free cash flow of −$22.4M.

Questions

What was Taysha Gene Therapies' revenue in the first quarter 2025?

Taysha Gene Therapies (TSHA) reported revenue of $2.3M for the first quarter 2025 (Q1 2025), -33% from a year earlier and +14% from the quarter before.

Was Taysha Gene Therapies profitable in the first quarter 2025?

Operating loss was $21.4M (-930.5% of revenue) and net loss $21.5M.

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Source: Taysha Gene Therapies 10-Q on SEC EDGAR.