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Upstream Bio (UPB) earnings on Nov 10, 2026: what to expect

Upstream Bio (UPB) is expected to report earnings on Nov 10, 2026 (estimated), in 2 days, for the quarter ending Sep 30, 2026. Analysts expect EPS of −$0.73 (−$0.88 to −$0.52, 8 estimates) on revenue of $480K, against −$0.63 and $683K a year ago. It beat the EPS estimate in 75% of the quarters on record; Filing Flows' model gives it a 75% chance of beating next time.

Report dateNov 10, 2026 (estimated)
Days to go2
EPS estimate−$0.73
Revenue estimate$480K
Beat rate75%

What to watch

Last quarter (Q2 2026) the lines that make up revenue grew like this; the report shows whether the trend holds:

Upstream Bio: revenue lines, growth year over year, Q2 2026Upstream Bio: revenue lines, growth year over year, Q2 2026Revenue-18%

Filing Flows' own estimate from the SEC figures — the same quarter last year times recent growth — is EPS −$0.63 on revenue of $928K, against the analysts' −$0.73.

The last report

Upstream Bio reported revenue of $773K for the second quarter 2026 (-18% Y/Y), net loss $39.7M. How it makes money → · Every quarter →

Upstream Bio: EPS against the estimate, last 4 reportsUpstream Bio: EPS against the estimate, last 4 reportsEstimateReported−$0.78−$0.63Nov 25−$0.70−$0.78Mar 26−$0.75−$0.75May 26−$0.76−$0.73Aug 26
Latest (Aug 26): Estimate −$0.76, Reported −$0.73.

Upstream Bio's latest quarter

Upstream Bio, Q2 2026: revenue $773K (-18% year over year), net loss $39.7M, operating cash flow −$35.6M. The chart follows the revenue to costs, profit and cash.

Questions

When does UPB report earnings?

Upstream Bio is expected to report on Nov 10, 2026 (estimated).

What are analysts expecting from Upstream Bio?

EPS of −$0.73 and revenue of $480K for the quarter.

Does Upstream Bio usually beat earnings?

It beat the consensus EPS estimate in 75% of the quarters on record.

Open the interactive view →

Updated Nov 8, 2026. Read automatically from SEC filings and public data; errors are possible. Not investment advice.