Filing Flows › Veracyte (VCYT) › Q4 2025
Veracyte (VCYT) Q4 2025 earnings results (fourth quarter 2025)
10-K filed Feb 26, 2026
Veracyte (VCYT) reported revenue of $141M for the fourth quarter 2025 (Q4 2025), +19% from a year earlier and +7% from the quarter before. Operating margin was 26.4%, net earnings $41.1M (29.3% of revenue).
Veracyte, Q4 2025: revenue $141M (+18% year over year), operating margin 26.4%, net earnings $41.1M, operating cash flow $52.6M. The chart follows the revenue to costs, profit and cash.
| Q4 2025 | Amount | Q/Q | Y/Y |
|---|---|---|---|
| Revenue | $141M | +7% | +19% |
| Gross profit | $102M | +12% | +29% |
| Operating profit | $37.2M | +62% | +791% |
| Net earnings | $41.1M | +115% | +705% |
| Operating cash flow | $52.6M | +17% | +114% |
| Free cash flow | $48.8M | +16% | +139% |
What changed
Revenue was $140.6M in Q4 2025, up 19% year over year and up 7% from the previous quarter. Testing revenue was the largest line at 97% of revenue.
Gross margin was 72.5%, up 6.1 points from a year earlier. Operating profit was $37.2M, a 26.4% margin (up 22.9 points year over year). Of the extra revenue versus a year earlier, 150% reached operating profit, above the 4% margin then. Operating expenses fell 13% while revenue rose 19%. Net earnings were $41.1M, up 705% year over year. The effective tax rate was -1.3%.
Operating cash flow was $52.6M (up 114% year over year), 128% of net earnings. Non-cash charges added back $5.3M of depreciation and amortization and $10.9M of share-based compensation. Working capital and other items used $4.8M. Capital expenditures of $3.8M left free cash flow of $48.8M.
Questions
What was Veracyte's revenue in the fourth quarter 2025?
Veracyte (VCYT) reported revenue of $141M for the fourth quarter 2025 (Q4 2025), +19% from a year earlier and +7% from the quarter before.
Was Veracyte profitable in the fourth quarter 2025?
Operating profit was $37.2M (26.4% of revenue) and net earnings $41.1M.
Source: Veracyte 10-K on SEC EDGAR.