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Xenetic Biosciences (XBIO) Q4 2025 earnings results (fourth quarter 2025)

10-K filed Mar 12, 2026

Xenetic Biosciences (XBIO) reported revenue of $766K for the fourth quarter 2025 (Q4 2025), +18% from a year earlier and -25% from the quarter before. Operating margin was -81.3%, net loss $579K (75.6% of revenue).

Revenue$766K
Year over year+18%
Quarter over quarter-25%
Operating margin-81.3%
Net earnings−$579K

Xenetic Biosciences, Q4 2025: revenue $766K (+18% year over year), operating margin -81.3%, net loss $579K, operating cash flow −$243K. The chart follows the revenue to costs, profit and cash.

Q4 2025AmountQ/QY/Y
Revenue$766K-25%+18%
Operating profit−$623K——
Net earnings−$579K——
Operating cash flow−$243K——

What changed

Revenue was $766K in Q4 2025, up 18% year over year and down 25% from the previous quarter.

Operating costs exceeded revenue by $623K, an operating margin of -81.3%. Total costs fell 21% while revenue rose 18%. The quarter ended with a net loss of $579K, wider than the previous quarter's $510K loss.

Operating cash flow was −$243K. Non-cash charges added back $14K of share-based compensation. Working capital and other items added $322K.

Questions

What was Xenetic Biosciences' revenue in the fourth quarter 2025?

Xenetic Biosciences (XBIO) reported revenue of $766K for the fourth quarter 2025 (Q4 2025), +18% from a year earlier and -25% from the quarter before.

Was Xenetic Biosciences profitable in the fourth quarter 2025?

Operating loss was $623K (-81.3% of revenue) and net loss $579K.

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Source: Xenetic Biosciences 10-K on SEC EDGAR.