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Avalo Therapeutics vs Clene: AVTX and CLNN compared

Avalo Therapeutics is the larger company: $59K of revenue in its latest quarter (Q4 2025) against $56K for Clene (Q3 2026). Clene is growing faster (+273% against -69% a year earlier).

Avalo Therapeutics vs Clene, latest quarterAvalo Therapeutics vs Clene, latest quarterAvalo Therapeutics (AVTX)Clene (CLNN)Revenue$59K$56KRevenue growth, Y/Y-69%+273%Operating marginn/mn/m

Where the money goes: AVTX and CLNN

Avalo Therapeutics (AVTX) · Q4 2025

Avalo Therapeutics, Q4 2025: revenue $59K (-69% year over year), net loss $13.7M, operating cash flow −$14.2M. The chart follows the revenue to costs, profit and cash.

Clene (CLNN) · Q3 2026

Clene, Q3 2026: revenue $56K (+273% year over year), net earnings $3.9M, operating cash flow −$4.6M. The chart follows the revenue to costs, profit and cash.

Clene revenue by segment, Q3 2026Clene revenue by segment, Q3 2026Product$43KRoyalty$13K
Avalo Therapeutics (AVTX)Clene (CLNN)
Latest quarterQ4 2025Q3 2026
Revenue$59K$56K
Revenue growth, Y/Y-69%+273%
Operating marginn/mn/m
Net earnings−$13.7M$3.9M
Operating cash flow−$14.2M−$4.6M
Market value$595M—
Analysts’ mean target$36.60—

Where the revenue comes from

Clene

Questions

Which is bigger, Avalo Therapeutics or Clene?

Avalo Therapeutics is the larger company: $59K of revenue in its latest quarter (Q4 2025) against $56K for Clene (Q3 2026).

Is Avalo Therapeutics or Clene growing faster?

Clene is growing faster (+273% against -69% a year earlier).

More: Avalo Therapeutics earnings · how Avalo Therapeutics makes money · Clene earnings · how Clene makes money

From the companies' latest 10-Q, 10-K or earnings release (10-K filed Mar 23, 2026; 10-Q filed Nov 4, 2026). Fiscal quarters can end on different dates. Not investment advice.