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Guardant Health vs Caris Life Sciences: GH and CAI compared
Guardant Health is the larger company: $361M of revenue in its latest quarter (Q3 2026) against $275M for Caris Life Sciences (Q3 2026). Guardant Health is growing faster (+36% against +27% a year earlier). Caris Life Sciences is more profitable, with an operating margin of 7.0% against -36.8%.
Where the money goes: GH and CAI
Guardant Health (GH) · Q3 2026
Guardant Health, Q3 2026: revenue $361M (+36% year over year), operating margin -36.8%, net loss $124M, operating cash flow −$23.7M. The chart follows the revenue to costs, profit and cash.
Caris Life Sciences (CAI) · Q3 2026
Caris Life Sciences, Q3 2026: revenue $275M (+27% year over year), operating margin 7.0%, net earnings $15.2M, operating cash flow −$22.2M. The chart follows the revenue to costs, profit and cash.
| Guardant Health (GH) | Caris Life Sciences (CAI) | |
|---|---|---|
| Latest quarter | Q3 2026 | Q3 2026 |
| Revenue | $361M | $275M |
| Revenue growth, Y/Y | +36% | +27% |
| Operating margin | -36.8% | 7.0% |
| Net earnings | −$124M | $15.2M |
| Net margin | -34.5% | 5.5% |
| Operating cash flow | −$23.7M | −$22.2M |
| Market value | $20.3B | — |
| Analysts’ mean target | $200.84 | — |
Where the revenue comes from
Guardant Health
- Oncology: $231M (64%)
- Screening: $67.6M (19%)
- Biopharma and data: $59.0M (16%)
- Licensing and other: $3.1M (1%)
Caris Life Sciences
- Molecular Profiling Services: $263M (95%)
- Pharma Research and Development Services: $12.7M (5%)
Questions
Which is bigger, Guardant Health or Caris Life Sciences?
Guardant Health is the larger company: $361M of revenue in its latest quarter (Q3 2026) against $275M for Caris Life Sciences (Q3 2026).
Is Guardant Health or Caris Life Sciences growing faster?
Guardant Health is growing faster (+36% against +27% a year earlier).
Which is more profitable, Guardant Health or Caris Life Sciences?
Caris Life Sciences is more profitable, with an operating margin of 7.0% against -36.8%.
More: Guardant Health earnings · how Guardant Health makes money · Caris Life Sciences earnings · how Caris Life Sciences makes money
From the companies' latest 10-Q, 10-K or earnings release (10-Q filed Nov 5, 2026; 10-Q filed Nov 4, 2026). Fiscal quarters can end on different dates. Not investment advice.