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Grail vs Personalis: GRAL and PSNL compared
Grail is the larger company: $37.5M of revenue in its latest quarter (Q3 2026) against $25.6M for Personalis (Q3 2026). Personalis is growing faster (+77% against +4% a year earlier). Personalis is more profitable, with an operating margin of -138.8% against -385.3%.
Where the money goes: GRAL and PSNL
Grail (GRAL) · Q3 2026
Grail, Q3 2026: revenue $37.5M (+4% year over year), operating margin -385.3%, net loss $104M, operating cash flow −$74.7M. The chart follows the revenue to costs, profit and cash.
Personalis (PSNL) · Q3 2026
Personalis, Q3 2026: revenue $25.6M (+77% year over year), operating margin -138.8%, net loss $33.8M, operating cash flow −$27.1M. The chart follows the revenue to costs, profit and cash.
| Grail (GRAL) | Personalis (PSNL) | |
|---|---|---|
| Latest quarter | Q3 2026 | Q3 2026 |
| Revenue | $37.5M | $25.6M |
| Revenue growth, Y/Y | +4% | +77% |
| Operating margin | -385.3% | -138.8% |
| Net earnings | −$104M | −$33.8M |
| Net margin | -275.9% | -132.1% |
| Operating cash flow | −$74.7M | −$27.1M |
| Market value | $6.0B | — |
| Analysts’ mean target | $132.56 | — |
Where the revenue comes from
Grail
- Screening revenue: $37.3M (99%)
- Development Services: $266K (1%)
Questions
Which is bigger, Grail or Personalis?
Grail is the larger company: $37.5M of revenue in its latest quarter (Q3 2026) against $25.6M for Personalis (Q3 2026).
Is Grail or Personalis growing faster?
Personalis is growing faster (+77% against +4% a year earlier).
Which is more profitable, Grail or Personalis?
Personalis is more profitable, with an operating margin of -138.8% against -385.3%.
More: Grail earnings · how Grail makes money · Personalis earnings · how Personalis makes money
From the companies' latest 10-Q, 10-K or earnings release (10-Q filed Nov 5, 2026; 10-Q filed Nov 4, 2026). Fiscal quarters can end on different dates. Not investment advice.