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Harmony Biosciences Holdings vs Axsome Therapeutics: HRMY and AXSM compared
Harmony Biosciences Holdings is the larger company: $269M of revenue in its latest quarter (Q3 2026) against $260M for Axsome Therapeutics (Q3 2026). Axsome Therapeutics is growing faster (+52% against +12% a year earlier). Harmony Biosciences Holdings is more profitable, with an operating margin of 20.2% against -4.3%.
Where the money goes: HRMY and AXSM
Harmony Biosciences Holdings (HRMY) · Q3 2026
Harmony Biosciences Holdings, Q3 2026: revenue $269M (+12% year over year), operating margin 20.2%, net earnings $48.2M, operating cash flow $76.7M. The chart follows the revenue to costs, profit and cash.
Axsome Therapeutics (AXSM) · Q3 2026
Axsome Therapeutics, Q3 2026: revenue $260M (+52% year over year), operating margin -4.3%, net loss $12.9M, operating cash flow −$9.5M. The chart follows the revenue to costs, profit and cash.
| Harmony Biosciences Holdings (HRMY) | Axsome Therapeutics (AXSM) | |
|---|---|---|
| Latest quarter | Q3 2026 | Q3 2026 |
| Revenue | $269M | $260M |
| Revenue growth, Y/Y | +12% | +52% |
| Gross margin | 70.0% | — |
| Operating margin | 20.2% | -4.3% |
| Net earnings | $48.2M | −$12.9M |
| Net margin | 17.9% | -5.0% |
| Operating cash flow | $76.7M | −$9.5M |
| Market value | — | $8.8B |
| Analysts’ mean target | — | $265.86 |
Where the revenue comes from
Axsome Therapeutics
- Product: $250M (96%)
- Royalty and Milestone Revenue: $9.7M (4%)
Questions
Which is bigger, Harmony Biosciences Holdings or Axsome Therapeutics?
Harmony Biosciences Holdings is the larger company: $269M of revenue in its latest quarter (Q3 2026) against $260M for Axsome Therapeutics (Q3 2026).
Is Harmony Biosciences Holdings or Axsome Therapeutics growing faster?
Axsome Therapeutics is growing faster (+52% against +12% a year earlier).
Which is more profitable, Harmony Biosciences Holdings or Axsome Therapeutics?
Harmony Biosciences Holdings is more profitable, with an operating margin of 20.2% against -4.3%.
More: Harmony Biosciences Holdings earnings · how Harmony Biosciences Holdings makes money · Axsome Therapeutics earnings · how Axsome Therapeutics makes money
From the companies' latest 10-Q, 10-K or earnings release (10-Q filed Nov 4, 2026; 10-Q filed Nov 2, 2026). Fiscal quarters can end on different dates. Not investment advice.