Filing Flows

Filing Flows › Health Care › Axsome Therapeutics (AXSM)

Axsome Therapeutics (AXSM) earnings and revenue breakdown

Latest: Q3 2026 · 10-Q filed Nov 2, 2026 · Axsome Therapeutics (AXSM) Q3 2026 earnings results →

Q3 2026 Revenue up 52% year over year to $260M · 5¢ of every $1 of revenue lost · operating margin -4.3%

Axsome Therapeutics made $260M in Q3 2026 (+52% Y/Y): Product $250M, Royalty and Milestone Revenue $9.7M. Operating margin -4.3%, net loss $12.9M. See where every dollar goes — costs, profit and cash — as a Sankey from the 10-Q filed Nov 2, 2026.

Revenue$260M
Year over year+52%
Operating margin-4.3%
Net earnings−$12.9M
Operating cash flow−$9.5M

Drawing the Sankey…

Open the interactive Sankey → click any line for what the company wrote about it, compare Y/Y and Q/Q, export as PNG or PDF

What changed this quarter

Revenue was $259.7M in Q3 2026, up 52% year over year and up 19% from the previous quarter. Product was the largest line at 96% of revenue. Product added $80.2M year over year (up 47%), 90% of the total change.

Operating costs exceeded revenue by $11.1M, an operating margin of -4.3%. Total costs grew 25% against revenue growth of 52%. The fastest-growing cost line was Cost of revenue (+49%). The quarter ended with a net loss of $12.9M, narrower than the previous quarter's $51.3M loss.

Operating cash flow was −$9.5M. Non-cash charges added back $1.7M of depreciation and amortization and $26.4M of share-based compensation. Working capital and other items used $24.7M. Capital expenditures of $197K exceeded it, leaving free cash flow of −$9.7M.

Quarterly history

Axsome Therapeutics revenue by quarterAxsome Therapeutics revenue by quarter$121MQ1 2025$150MQ2 2025$171MQ3 2025$196MQ4 2025$191MQ1 2026$218MQ2 2026$260MQ3 2026
Axsome Therapeutics net earnings by quarterAxsome Therapeutics net earnings by quarter−$59.4MQ1 2025−$48.0MQ2 2025−$47.2MQ3 2025−$28.6MQ4 2025−$64.5MQ1 2026−$51.3MQ2 2026−$12.9MQ3 2026
QuarterFormFiledRevenueY/YOp. marginNet earningsOp. cash flow
Q3 202610-QNov 2, 2026$260M+52%-4.3%−$12.9M−$9.5M
Q2 202610-QAug 10, 2026$218M+46%-22.7%−$51.3M−$33.0M
Q1 202610-QMay 4, 2026$191M+57%-33.1%−$64.5M−$20.7M
Q4 202510-KFeb 23, 2026$196M+65%-13.8%−$28.6M−$18.7M
Q3 202510-QNov 3, 2025$171M+63%-27.0%−$47.2M$1.0M
Q2 202510-QAug 4, 2025$150M+72%-24.5%−$48.0M−$32.4M
Q1 202510-QMay 5, 2025$121M+62%-46.9%−$59.4M−$43.4M

Charts

Axsome Therapeutics: revenue growth, year over year and quarter over quarterAxsome Therapeutics: revenue growth, year over year and quarter over quarterY/YQ/Q+62%Q1 2025+72%+24%Q2 2025+63%+14%Q3 2025+65%+15%Q4 2025+57%-2%Q1 2026+46%+14%Q2 2026+52%+19%Q3 2026
Latest (Q3 2026): Y/Y +52%, Q/Q +19%.
Axsome Therapeutics: where the cash came from (+) and went (−), TTM to Q3 2026Axsome Therapeutics: where the cash came from (+) and went (−), TTM to Q3 2026Operating cash flow−$81.8MOther financing$64.6MShares issued$25.5MTaxes on employees’ shares−$15.0MCash drawn (+) / kept (−)$11.4MNet borrowing (+) / repaid (−)−$3.8MCapital spending−$839K
From the cash-flow statement as filed (SEC XBRL). Cash is fungible: the bars do not say which dollar paid for what.
Axsome Therapeutics: profit against cash, quarter by quarterAxsome Therapeutics: profit against cash, quarter by quarterNet incomeOperating cash flow−$74.9M−$26.2MQ4 2024−$59.4M−$43.4MQ1 2025−$48.0M−$32.4MQ2 2025−$47.2M$1.0MQ3 2025−$28.6M−$18.7MQ4 2025−$64.5M−$20.7MQ1 2026−$51.3M−$33.0MQ2 2026−$12.9M−$9.5MQ3 2026
Latest (Q3 2026): Net income −$12.9M, Operating cash flow −$9.5M.
Axsome Therapeutics: diluted shares by fiscal yearAxsome Therapeutics: diluted shares by fiscal year37MFY202038MFY202141MFY202245MFY202348MFY202450MFY2025
+33.7% since FY2020: more shares outstanding (issuance, stock pay).
Axsome Therapeutics in its industry: growth against margin (225 companies, SIC 2834)Axsome Therapeutics in its industry: growth against margin (225 companies, SIC 2834)revenue growth, year over year →↑ operating marginmedian +11%median -50%JNJLLYMRKABBVPFEBMYABTREGNTEVAVTRSVRTXBHCZTSONCOGNALNYELANJAZZBMRNPRGOAMRXUTHRRPRXNRIXINSMKeenova Therapeutics plcALKSMDGLPAHCSRPTPTCTINDVBBIOACADCORTPBHANIPKNSAPTGXHRMYIONSTGTXSUPNTVTXCOLLVREOFAMPHMIRMPCRXRARELQDAARQTIRWDARDXNATRXNCREBSZLABXERSINVACRMDMNKDRYTMURGNPHATAUPHSNDXRIGLLGNDEOLSARWRPGENHROWVNDAOPKSDGRGERNETONAGIOPBYITNGXCYRXCYTKMRVIORGONUVBLFVNSIGAKROSAMRNZVRASPRYHRTXAKBABCYCKPTIGYREMGNXELTPSEPNVRDNLFCRCrinetics Pharmaceuticals, Inc.VSTMKURATBPHLABADCTNAMSFBIOXLODERMARCTRMTIAYTUFHTXENTATNXPOCULASMBWVEAPMDBFRIABEOSTOKLXRXCAPRIDYANKTRZOMDFINBPJANXSBFMGOSSETSTRCUSCPIXLIFDCUEAQSTPRAXWHWKVERUEMMAGENBVRCACELUQUREZYMEEQABCLIMNMKYNBAKTSRNACVSICNTBTRAWISCOEVFMTVRDLPCNCAMPAtaiBeckley Inc.CTMXALMSPMHSACRSVTGNROIVKRROJAGXENSCKRSAABUSPRPHSTTKCPHITRDATXMDGOVXNWBOBIOEUPBIRDOVIDSPRBXBIOPRTAMCRBARVNMNOVSLNIGCBIOALGVNDNTHCPMDSPRORFLCOYASCYXBFRGSXTPBTAIQHCWBSERYARWRNACRGBPAVTXCLNNNTHIHINDAAGHALTONCOCRVOSKVIBOLTBDPTLYELIBOPULMAXSM (+52%, -4%)
Pharmaceutical Preparations; dot size is quarterly revenue; dashed lines are the industry's medians.

Interactive views

The same charts as the app — open one to draw it.

💵Where each $1 goesinteractive

Loading the interactive chart…

🌏Named in Asian annual reportsinteractive

Loading the interactive chart…

🔄Rotation against the market and its industry (RRG)interactive

Loading the interactive chart…

🔍Earnings qualityinteractive

Loading the interactive chart…

⚖️Fair value by methodinteractive

Loading the interactive chart…

🔭Outlook & guidanceinteractive

Loading the interactive chart…

📈Investments: gains and what it boughtinteractive

Loading the interactive chart…

🏭Its industry’s money flow (input-output)interactive

Loading the interactive chart…

About Axsome Therapeutics

Axsome Therapeutics is a biopharmaceutical company leading a new era in the treatment of central nervous system (CNS) conditions. We deliver scientific breakthroughs by identifying critical gaps in care and develop differentiated products with a focus on novel mechanisms of action that enable meaningful advancements in patient outcomes. Our industry-leading neuroscience portfolio includes FDA-approved treatments for major depressive disorder, agitation associated with dementia due to Alzheimer’s disease, excessive daytime sleepiness associated with narcolepsy and obstructive sleep apnea, and migraine, as well as multiple novel product candidates addressing a broad range of serious neurological and psychiatric conditions that impact over 150 million people in the United States.

In its own words, from its 8-K, filed Aug 10, 2026.

Axsome Therapeutics against its Pharmaceutical Preparations peers

The largest companies of the same SEC industry, each at its latest quarter. Revenue growth: +52% against the peers' median +10%. Operating margin: -4.3% against the peers' median 20.4%.

CompanyQuarterRevenueY/YOp. margin
AXSM Axsome TherapeuticsQ3 2026$260M+52%-4.3%
JNJ Johnson & JohnsonQ3 2026$25.4B+6%0.1%
LLY ELI LillyQ3 2026$24.4B+39%34.5%
MRK MerckQ3 2026$18.1B+5%30.7%
ABBV AbbVieQ3 2026$17.4B+10%36.0%
PFE PfizerQ3 2026$16.6B-0.4%20.4%
BMY Bristol Myers SquibbQ3 2026$13.1B+7%19.4%
ABT Abbott LaboratoriesQ3 2026$13.0B+14%10.4%
REGN Regeneron PharmaceuticalsQ3 2026$5.1B+36%40.0%

Source: Axsome Therapeutics 10-Q on SEC EDGAR · CIK 1579428 · Pharmaceutical Preparations

Guidance and outlook

Axsome Therapeutics: what its forward-looking statements are about (10-Q filed 2026-11-02)Axsome Therapeutics: what its forward-looking statements are about (10-Q filed 2026-11-02)Other7Demand6Costs4Legal & regulation2Margins1Financing1
21 statements; tone +0.05 (−1 all cautious, +1 all confident); 5 hedged.
Axsome Therapeutics: outlook statements against the filing beforeAxsome Therapeutics: outlook statements against the filing beforeConfident4Cautious3

13F: who owns AXSM and who is buying

Largest holders of AXSM (13F)Largest holders of AXSM (13F)Vanguard Group$761MBlackRock$760MVanguard Portfolio Management LLC$486MVanguard Capital Management LLC$481MInvesco$409MFMR LLC$377MGeode Capital Management, LLC$237MMorgan Stanley$197MState Street$192MDeep Track Capital, LP$171M
Funds' net buying of AXSM by quarter (13F)Funds' net buying of AXSM by quarter (13F)−$131M2024-09−$170M2024-12$22.1M2025-03$23.3M2025-06−$39.0M2025-09−$205M2025-12$99.2M2026-03$12.6M2026-06
Value of shares 13F filers added minus the value they sold, each quarter (quarters with most filings in).

More on AXSM

History

Every quarter: Q3 2026 results · Q2 2026 results · Q1 2026 results · Q4 2025 results · Q3 2025 results · Q2 2025 results · Q1 2025 results

Compare AXSM with

中文版:Axsome Therapeutics(AXSM)财报

Español · Français