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Axsome Therapeutics (AXSM) Q1 2026 earnings results (first quarter 2026)

10-Q filed May 4, 2026

Axsome Therapeutics (AXSM) reported revenue of $191M for the first quarter 2026 (Q1 2026), +57% from a year earlier and -2% from the quarter before. Operating margin was -33.1%, net loss $64.5M (33.8% of revenue).

Revenue$191M
Year over year+57%
Quarter over quarter-2%
Operating margin-33.1%
Net earnings−$64.5M

Axsome Therapeutics, Q1 2026: revenue $191M (+57% year over year), operating margin -33.1%, net loss $64.5M, operating cash flow −$20.7M. The chart follows the revenue to costs, profit and cash.

Q1 2026AmountQ/QY/Y
Revenue$191M-2%+57%
Operating profit−$63.4M——
Net earnings−$64.5M——
Operating cash flow−$20.7M——

What changed

Revenue was $191.2M in Q1 2026, up 57% year over year and down 2% from the previous quarter. Product was the largest line at 99% of revenue. Product added $69.0M year over year (up 57%), 99% of the total change.

Operating costs exceeded revenue by $63.4M, an operating margin of -33.1%. Total costs grew 43% against revenue growth of 57%. The fastest-growing cost line was SG&A (+53%). The quarter ended with a net loss of $64.5M, wider than the previous quarter's $28.6M loss.

Operating cash flow was −$20.7M. Non-cash charges added back $1.7M of depreciation and amortization and $23.4M of share-based compensation. Working capital and other items added $18.7M. Capital expenditures of $121K exceeded it, leaving free cash flow of −$20.8M.

Questions

What was Axsome Therapeutics' revenue in the first quarter 2026?

Axsome Therapeutics (AXSM) reported revenue of $191M for the first quarter 2026 (Q1 2026), +57% from a year earlier and -2% from the quarter before.

Was Axsome Therapeutics profitable in the first quarter 2026?

Operating loss was $63.4M (-33.1% of revenue) and net loss $64.5M.

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Source: Axsome Therapeutics 10-Q on SEC EDGAR.