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Axsome Therapeutics (AXSM) Q2 2026 earnings results (second quarter 2026)

10-Q filed Aug 10, 2026

Axsome Therapeutics (AXSM) reported revenue of $218M for the second quarter 2026 (Q2 2026), +46% from a year earlier and +14% from the quarter before. Operating margin was -22.7%, net loss $51.3M (23.5% of revenue).

Revenue$218M
Year over year+46%
Quarter over quarter+14%
Operating margin-22.7%
Net earnings−$51.3M

Axsome Therapeutics, Q2 2026: revenue $218M (+46% year over year), operating margin -22.7%, net loss $51.3M, operating cash flow −$33.0M. The chart follows the revenue to costs, profit and cash.

Q2 2026AmountQ/QY/Y
Revenue$218M+14%+46%
Operating profit−$49.6M——
Net earnings−$51.3M——
Operating cash flow−$33.0M——

What changed

Revenue was $218.4M in Q2 2026, up 46% year over year and up 14% from the previous quarter. Product was the largest line at 99% of revenue. Product added $67.4M year over year (up 45%), 99% of the total change.

Operating costs exceeded revenue by $49.6M, an operating margin of -22.7%. Total costs grew 44% against revenue growth of 46%. The quarter ended with a net loss of $51.3M, narrower than the previous quarter's $64.5M loss.

Operating cash flow was −$33.0M. Non-cash charges added back $1.7M of depreciation and amortization and $27.1M of share-based compensation. Working capital and other items used $10.5M. Capital expenditures of $450K exceeded it, leaving free cash flow of −$33.4M.

Questions

What was Axsome Therapeutics' revenue in the second quarter 2026?

Axsome Therapeutics (AXSM) reported revenue of $218M for the second quarter 2026 (Q2 2026), +46% from a year earlier and +14% from the quarter before.

Was Axsome Therapeutics profitable in the second quarter 2026?

Operating loss was $49.6M (-22.7% of revenue) and net loss $51.3M.

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Source: Axsome Therapeutics 10-Q on SEC EDGAR.