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Axsome Therapeutics (AXSM) Q1 2025 earnings results (first quarter 2025)

10-Q filed May 5, 2025

Axsome Therapeutics (AXSM) reported revenue of $121M for the first quarter 2025 (Q1 2025), +62% from a year earlier and +2% from the quarter before. Operating margin was -46.9%, net loss $59.4M (48.9% of revenue).

Revenue$121M
Year over year+62%
Quarter over quarter+2%
Operating margin-46.9%
Net earnings−$59.4M

Axsome Therapeutics, Q1 2025: revenue $121M (+62% year over year), operating margin -46.9%, net loss $59.4M, operating cash flow −$43.4M. The chart follows the revenue to costs, profit and cash.

Q1 2025AmountQ/QY/Y
Revenue$121M+2%+62%
Operating profit−$57.0M——
Net earnings−$59.4M——
Operating cash flow−$43.4M——

What changed

Revenue was $121.5M in Q1 2025, up 62% year over year and up 2% from the previous quarter. Product was the largest line at 99% of revenue. Product added $46.3M year over year (up 62%), 100% of the total change.

Operating costs exceeded revenue by $57.0M, an operating margin of -46.9%. Total costs grew 25% against revenue growth of 62%. The fastest-growing cost line was Cost of revenue (+55%). The quarter ended with a net loss of $59.4M, narrower than the previous quarter's $74.9M loss.

Operating cash flow was −$43.4M. Non-cash charges added back $1.7M of depreciation and amortization and $23.3M of share-based compensation. Working capital and other items used $9.0M. Capital expenditures of $338K exceeded it, leaving free cash flow of −$43.7M.

Questions

What was Axsome Therapeutics' revenue in the first quarter 2025?

Axsome Therapeutics (AXSM) reported revenue of $121M for the first quarter 2025 (Q1 2025), +62% from a year earlier and +2% from the quarter before.

Was Axsome Therapeutics profitable in the first quarter 2025?

Operating loss was $57.0M (-46.9% of revenue) and net loss $59.4M.

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Source: Axsome Therapeutics 10-Q on SEC EDGAR.